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Ailong Huang

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Articles 212
Citations 3561
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Recent Articles
1.
Wei J, Huang J, Zou C, Shen S, Kreiswirth B, Huang A, et al.
mSystems . 2025 Mar; :e0018425. PMID: 40067047
carbapenemases (KPCs) have evolved into over 245 distinct variants, with over one-third of variants exhibiting reduced susceptibility to ceftazidime-avibactam, while the underlying selection mechanisms remain elusive. To better elucidate these...
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Chang W, Feng K, Zhou P, Gong D, Wang K, Huang A, et al.
Cancer Sci . 2025 Feb; PMID: 39962908
Tumor necrosis factor receptor-associated factor-6 (TRAF6) is a well-established upstream regulator of the IKK complex, essential for the modulation of the NF-κB (nuclear factor kappa B) signaling pathway. Aberrant activation...
4.
Ren J, Cheng S, Ren F, Gu H, Wu D, Yao X, et al.
Genes Dis . 2024 Nov; 12(1):101215. PMID: 39534573
Human hepatitis B virus (HBV) infection is the major cause of acute and chronic hepatitis B, liver cirrhosis, and hepatocellular carcinoma. Although the application of prophylactic vaccination programs has successfully...
5.
Shen S, Wang W, Ma Y, Wang S, Zhang S, Cai X, et al.
Nat Commun . 2024 Oct; 15(1):9304. PMID: 39468064
Invasive fungal infections (IFIs) pose a significant threat to immunocompromised individuals, leading to considerable morbidity and mortality. Prompt and accurate diagnosis is essential for effective treatment. Here we develop a...
6.
Liu Y, Yang J, Wang Y, Zeng Q, Fan Y, Huang A, et al.
Genes Dis . 2024 Sep; 11(6):101142. PMID: 39281837
Chronic hepatitis B virus (HBV) infection is a leading cause of liver cirrhosis and hepatocellular carcinoma, representing a global health problem for which a functional cure is difficult to achieve....
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Zeng Q, Ren Y, Wang Y, Yang J, Qin Y, Yang L, et al.
J Med Virol . 2024 Jul; 96(7):e29805. PMID: 39011773
Heterogeneous nuclear protein U (HNRNPU) plays a pivotal role in innate immunity by facilitating chromatin opening to activate immune genes during host defense against viral infection. However, the mechanism by...
8.
Yu H, Ren J, Deng H, Li L, Zhang Z, Cheng S, et al.
J Hepatol . 2024 Jul; 82(1):37-50. PMID: 38960374
Background & Aims: Sodium taurocholate cotransporting polypeptide (NTCP) has been identified as the cellular receptor for HBV. However, hepatocytes expressing NTCP exhibit varying susceptibilities to HBV infection. This study aimed...
9.
Hu Y, Peng B, Fan J, Yang Z, Xue J, Long Q, et al.
Genes Dis . 2024 Jun; 11(5):101151. PMID: 38882010
No abstract available.
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Qin Y, Ren J, Yu H, He X, Cheng S, Chen W, et al.
Adv Sci (Weinh) . 2024 Apr; 11(24):e2306810. PMID: 38647380
Persistent transcription of HBV covalently closed circular DNA (cccDNA) is critical for chronic HBV infection. Silencing cccDNA transcription through epigenetic mechanisms offers an effective strategy to control HBV. Long non-coding...