Stephen Francis
Overview
Explore the profile of Stephen Francis including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
3095
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0
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Recent Articles
11.
Shah N, Kantarjian H, Kim D, Rea D, Dorlhiac-Llacer P, Milone J, et al.
J Clin Oncol
. 2008 Jun;
26(19):3204-12.
PMID: 18541900
Purpose: Dasatinib is a BCR-ABL inhibitor, 325-fold more potent than imatinib against unmutated BCR-ABL in vitro. Phase II studies have demonstrated efficacy and safety with dasatinib 70 mg twice daily...
12.
Dowsett M, Smith I, Ebbs S, Dixon J, Skene A, Griffith C, et al.
Clin Cancer Res
. 2006 Feb;
12(3 Pt 2):1024s-1030s.
PMID: 16467120
The study of changes in proliferation as a marker of treatment benefit during presurgical endocrine treatment of breast cancer has become increasingly popular, particularly using the nuclear marker Ki67, and...
13.
Smith I, Dowsett M, Ebbs S, Dixon J, Skene A, Blohmer J, et al.
J Clin Oncol
. 2005 Jul;
23(22):5108-16.
PMID: 15998903
Purpose: The Immediate Preoperative Anastrozole, Tamoxifen, or Combined With Tamoxifen (IMPACT) trial was designed to test the hypothesis that the clinical and/or biologic effects of neoadjuvant tamoxifen compared with anastrozole...
14.
Dowsett M, Ebbs S, Dixon J, Skene A, Griffith C, Boeddinghaus I, et al.
J Clin Oncol
. 2005 Mar;
23(11):2477-92.
PMID: 15767642
Purpose: To investigate the relationships between biomarker changes in breast cancer during neoadjuvant (preoperative) endocrine therapy. Patients And Methods: The IMPACT trial compared the preoperative use of tamoxifen with anastrozole...
15.
Dowsett M, Smith I, Ebbs S, Dixon J, Skene A, Griffith C, et al.
Clin Cancer Res
. 2005 Feb;
11(2 Pt 2):951s-8s.
PMID: 15701892
Purpose: Neoadjuvant (preoperative) therapy for breast cancer may allow for the development of intermediate markers of treatment benefit, thereby circumventing the need for efficacy trials of adjuvant therapy, which require...
16.
Ang A, Taguchi T, Francis S, Folsch H, Murrells L, Pypaert M, et al.
J Cell Biol
. 2004 Nov;
167(3):531-43.
PMID: 15534004
The AP-1B clathrin adaptor complex is responsible for the polarized transport of many basolateral membrane proteins in epithelial cells. Localization of AP-1B to recycling endosomes (REs) along with other components...
17.
Fallowfield L, Cella D, Cuzick J, Francis S, Locker G, Howell A
J Clin Oncol
. 2004 Oct;
22(21):4261-71.
PMID: 15514369
Purpose: To determine the quality of life (QoL) of women participating in the Arimidex, Tamoxifen, Alone or in Combination (ATAC) Adjuvant Breast Cancer Trial during the first 2 years of...