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Stephen Dewhurst

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Articles 132
Citations 2734
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Recent Articles
1.
Hinkle J, Trychta K, Wires E, Osborn R, Leach J, Faraz Z, et al.
J Mol Histol . 2025 Mar; 56(2):98. PMID: 40025386
SARS-CoV-2 E and 3a proteins are important for the assembly, budding, and release of viral particles. These two transmembrane proteins have been implicated in forming channels in the membrane that...
2.
Abdelmageed A, Dewhurst S, Ferran M
Viruses . 2025 Jan; 17(1). PMID: 39861805
Vesicular Stomatitis Virus (VSV) has emerged as a promising candidate for various clinical applications, including vaccine development, virus pseudotyping, and gene delivery. Its broad host range, ease of propagation, and...
3.
Osborn R, Anderson C, Leach J, Chu C, Dewhurst S, Mariani T, et al.
Clin Exp Immunol . 2025 Jan; PMID: 39780400
Introduction: The ability of SARS-CoV-2 to evade antiviral immune signaling in the airway contributes to the severity of COVID-19 disease. Additionally, COVID-19 is influenced by age and has more severe...
4.
Alcantara Sanchez L, Alvarez Guerra E, Li D, King S, Hilchey S, Zhou Q, et al.
Vaccines (Basel) . 2025 Jan; 12(12. PMID: 39771974
: The global COVID-19 pandemic has resulted in approximately 7 million deaths and a historic vaccination effort, with over 13.6 billion doses administered. Despite this, understanding of immune responses in...
5.
Zand M, Spallina S, Ross A, Zandi K, Pawlowski A, Seplaki C, et al.
PLoS One . 2024 Nov; 19(11):e0313792. PMID: 39514527
[This corrects the article DOI: 10.1371/journal.pone.0291840.].
6.
Rahman S, Buchholz D, Imbiakha B, Jager M, Leach J, Osborn R, et al.
J Virol . 2024 May; 98(7):e0006624. PMID: 38814068
COVID-19 can cause neurological symptoms such as fever, dizziness, and nausea. However, such neurological symptoms of SARS-CoV-2 infection have been hardly assessed in mouse models. In this study, we infected...
7.
Zand M, Spallina S, Ross A, Zandi K, Pawlowski A, Seplaki C, et al.
PLoS One . 2024 Apr; 19(4):e0291840. PMID: 38568915
Background: This study examined the correlation of classroom ventilation (air exchanges per hour (ACH)) and exposure to CO2 ≥1,000 ppm with the incidence of SARS-CoV-2 over a 20-month period in...
8.
Imbiakha B, Sahler J, Buchholz D, Ezzatpour S, Jager M, Choi A, et al.
Sci Adv . 2024 Jan; 10(1):eadg5461. PMID: 38170764
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the ongoing global pandemic associated with morbidity and mortality in humans. Although disease severity correlates with immune dysregulation, the cellular mechanisms...
9.
Molina Vargas A, Sinha S, Osborn R, Arantes P, Patel A, Dewhurst S, et al.
Nucleic Acids Res . 2023 Nov; 52(2):921-939. PMID: 38033324
An increasingly pressing need for clinical diagnostics has required the development of novel nucleic acid-based detection technologies that are sensitive, fast, and inexpensive, and that can be deployed at point-of-care....
10.
Rahman S, Buchholz D, Imbiakha B, Jaeger M, Leach J, Osborn R, et al.
bioRxiv . 2023 Nov; PMID: 37965203
COVID-19 can result in neurological symptoms such as fever, headache, dizziness, and nausea. However, neurological signs of SARS-CoV-2 infection have been hardly assessed in mouse models. Here, we infected two...