Stephen C Harvey
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Explore the profile of Stephen C Harvey including associated specialties, affiliations and a list of published articles.
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70
Citations
2186
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Recent Articles
1.
Harris B, Harvey S
J Comput Chem
. 2022 May;
20(8):813-818.
PMID: 35619464
Knots can occur in real and model biological macromolecules. We describe a program for determining whether or not any knots are present in model structures and for classifying those knots...
2.
Mo Y, Keller N, delToro D, Ananthaswamy N, Harvey S, Rao V, et al.
Nucleic Acids Res
. 2020 Oct;
48(20):11602-11614.
PMID: 33119757
Many viruses employ ATP-powered motors during assembly to translocate DNA into procapsid shells. Previous reports raise the question if motor function is modulated by substrate DNA sequence: (i) the phage...
3.
Sharp K, Lu X, Cingolani G, Harvey S
Biophys J
. 2019 May;
116(11):2172-2180.
PMID: 31103227
Motors that move DNA, or that move along DNA, play essential roles in DNA replication, transcription, recombination, and chromosome segregation. The mechanisms by which these DNA translocases operate remain largely...
4.
Keul N, Oruganty K, Schaper Bergman E, Beattie N, McDonald W, Kadirvelraj R, et al.
Nature
. 2018 Nov;
563(7732):584-588.
PMID: 30420606
Protein structures are dynamic and can explore a large conformational landscape. Only some of these structural substates are important for protein function (such as ligand binding, catalysis and regulation). How...
5.
6.
Waters J, Kim H, Gumbart J, Lu X, Harvey S
J Phys Chem B
. 2016 May;
120(26):6200-7.
PMID: 27214211
The motors that drive double-stranded DNA (dsDNA) genomes into viral capsids are among the strongest of all biological motors for which forces have been measured, but it is not known...
7.
Waters J, Lu X, Galindo-Murillo R, Gumbart J, Kim H, Cheatham 3rd T, et al.
J Phys Chem B
. 2016 May;
120(33):8449-56.
PMID: 27135262
The structure of double-stranded DNA (dsDNA) is sensitive to solvent conditions. In solution, B-DNA is the favored conformation under physiological conditions, while A-DNA is the form found under low water...
8.
Petrov A, Gulen B, Norris A, Kovacs N, Bernier C, Lanier K, et al.
Proc Natl Acad Sci U S A
. 2015 Dec;
112(50):15396-401.
PMID: 26621738
We present a molecular-level model for the origin and evolution of the translation system, using a 3D comparative method. In this model, the ribosome evolved by accretion, recursively adding expansion...
9.
10.
Garmann R, Gopal A, Athavale S, Knobler C, Gelbart W, Harvey S
RNA
. 2015 Mar;
21(5):877-86.
PMID: 25752599
The lifecycle, and therefore the virulence, of single-stranded (ss)-RNA viruses is regulated not only by their particular protein gene products, but also by the secondary and tertiary structure of their...