Stephen C Bunnell
Overview
Explore the profile of Stephen C Bunnell including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
35
Citations
1634
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hopkins J, Sulka K, Sawden M, Carroll K, Brown R, Bunnell S, et al.
bioRxiv
. 2024 Apr;
PMID: 38645182
Local immune processes within aging tissues are a significant driver of aging associated dysfunction, but tissue-autonomous pathways and cell types that modulate these responses remain poorly characterized. The cytosolic DNA...
2.
Nguyen G, Xu S, Adams W, Leong J, Bunnell S, Mansour M, et al.
iScience
. 2021 Aug;
24(8):102871.
PMID: 34386732
Signaling cascades converting the recognition of pathogens to efficient inflammatory responses by neutrophils are critical for host survival. SKAP2, an adaptor protein, is required for reactive oxygen species (ROS) generation...
3.
Eidell K, Lovy A, Sylvain N, Scangarello F, Muendlein H, Ophir M, et al.
J Cell Sci
. 2021 Jul;
134(16).
PMID: 34279667
Integrin engagement within the immune synapse enhances T cell activation, but our understanding of this process is incomplete. In response to T cell receptor (TCR) ligation, SLP-76 (LCP2), ADAP (FYB1)...
4.
Nguyen G, Shaban L, Mack M, Swanson K, Bunnell S, Sykes D, et al.
Elife
. 2020 May;
9.
PMID: 32352382
is a respiratory, blood, liver, and bladder pathogen of significant clinical concern. We show that the adaptor protein, SKAP2, is required for protection against (ATCC 43816) pulmonary infections. - mice...
5.
Fray M, Charpentier J, Sylvain N, Seminario M, Bunnell S
J Cell Sci
. 2020 Jan;
133(5).
PMID: 31974114
Vav family guanine nucleotide exchange factors (GEFs) are essential regulators of immune function. Despite their structural similarity, Vav1 promotes and Vav2 opposes T cell receptor (TCR)-induced Ca entry. By using...
6.
Kalantari P, Bunnell S, Stadecker M
Front Immunol
. 2019 Feb;
10:26.
PMID: 30761125
Schistosomiasis is a major helminthic disease in which damage to the affected organs is orchestrated by a pathogenic host CD4 T helper (Th) cell-mediated immune response against parasite eggs. In...
7.
Sarhan J, Liu B, Muendlein H, Li P, Nilson R, Tang A, et al.
Proc Natl Acad Sci U S A
. 2018 Nov;
115(46):E10888-E10897.
PMID: 30381458
Cell death and inflammation are intimately linked during infection. Pathogenic inhibits the MAP kinase TGFβ-activated kinase 1 (TAK1) via the effector YopJ, thereby silencing cytokine expression while activating caspase-8-mediated cell...
8.
Lewis J, Scangarello F, Murphy J, Eidell K, Sodipo M, Ophir M, et al.
J Cell Sci
. 2018 Oct;
131(21).
PMID: 30305305
Antigen recognition by the T cell receptor (TCR) directs the assembly of essential signaling complexes known as SLP-76 (also known as LCP2) microclusters. Here, we show that the interaction of...
9.
Kalantari P, Morales Y, Miller E, Jaramillo L, Ponichtera H, Wuethrich M, et al.
Cell Rep
. 2018 Feb;
22(5):1288-1300.
PMID: 29386115
The immunopathology caused by schistosome helminths varies greatly in humans and among mouse strains. A severe form of parasite egg-induced hepatic granulomatous inflammation, seen in CBA mice, is driven by...
10.
Killpack T, Ballesteros M, Bunnell S, Bedugnis A, Kobzik L, Hu L, et al.
Infect Immun
. 2017 Jul;
85(10).
PMID: 28717031
Phagocytosis of the Lyme disease-causing pathogen has been shown to be important for generating an inflammatory response to the pathogen. As a result, understanding the mechanisms of phagocytosis has been...