Stephen B Doty
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Explore the profile of Stephen B Doty including associated specialties, affiliations and a list of published articles.
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54
Citations
1622
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Recent Articles
11.
Qu D, Subramony S, Boskey A, Pleshko N, Doty S, Lu H
J Orthop Res
. 2017 Feb;
35(11):2513-2523.
PMID: 28176356
The anterior cruciate ligament (ACL)-to-bone interface constitutes a complex, multi-tissue structure comprised of contiguous ligament, non-mineralized fibrocartilage, mineralized fibrocartilage, and bone regions. This composite structure enables load transfer between structurally...
12.
Blue M, Boskey A, Doty S, Fedarko N, Hossain M, Shapiro J
Bone
. 2015 Mar;
76:23-30.
PMID: 25769649
Rett syndrome (RTT) is an X-linked neurodevelopmental disorder due to mutations affecting the neural transcription factor MeCP2. Approximately 50% of affected females have decreased bone mass. We studied osteoblast function...
13.
Cushnie E, Ulery B, Nelson S, Deng M, Sethuraman S, Doty S, et al.
PLoS One
. 2014 Jul;
9(7):e101627.
PMID: 25019622
With greater than 500,000 orthopaedic procedures performed in the United States each year requiring a bone graft, the development of novel graft materials is necessary. We report that some porous...
14.
Dorai T, Diouri J, OShea O, Doty S
J Cancer Ther
. 2014 Jun;
5(4):369-386.
PMID: 24949215
A number of studies have focused on the beneficial properties of Curcumin (diferuloyl methane, used in South Asian cuisine and traditional medicine) such as the chemoprevention of cancer. Recent studies...
15.
Ciani C, Sharma D, Doty S, Fritton S
Bone
. 2013 Dec;
59:229-34.
PMID: 24316418
To test if osteoporosis alters mechanical load-induced interstitial fluid flow in bone, this study examined the combined effect of estrogen deficiency and external loading on solute transport around osteocytes. An...
16.
Palacio-Mancheno P, Larriera A, Doty S, Cardoso L, Fritton S
J Bone Miner Res
. 2013 Jun;
29(1):142-50.
PMID: 23775635
Current micro-computed tomography (µCT) systems allow scanning bone at resolutions capable of three-dimensional (3D) characterization of intracortical vascular porosity and osteocyte lacunae. However, the scanning and reconstruction parameters along with...
17.
Rapuano B, Singh H, Boskey A, Doty S, MacDonald D
J Cell Biochem
. 2013 Mar;
114(8):1917-27.
PMID: 23494951
It is believed that orthopedic and implant longevity can be improved by optimizing fixation, or direct bone-implant contact, through the stimulation of new bone formation around the implant. The purpose...
18.
Sharma D, Ciani C, Marin P, Levy J, Doty S, Fritton S
Bone
. 2012 May;
51(3):488-97.
PMID: 22634177
While reduced estrogen levels have been shown to increase bone turnover and induce bone loss, there has been little analysis of the effects of diminished estrogen levels on the lacunar-canalicular...
19.
Reumann M, Strachna O, Yagerman S, Torrecilla D, Kim J, Doty S, et al.
Bone
. 2011 Jul;
49(4):743-52.
PMID: 21726677
Transcription factors that play a role in ossification during development are expected to participate in postnatal fracture repair since the endochondral bone formation that occurs in embryos is recapitulated during...
20.
Zhu W, Liang G, Huang Z, Doty S, Boskey A
J Biol Chem
. 2011 Jun;
286(30):26794-805.
PMID: 21636574
Cysteine (C)-X-C motif chemokine receptor 4 (CXCR4), the primary receptor for stromal cell-derived factor-1 (SDF-1), is involved in bone morphogenic protein 2 (BMP2)-induced osteogenic differentiation of mesenchymal progenitors. To target...