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Stephen A Back

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Articles 71
Citations 4543
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Recent Articles
1.
Peters A, Banine F, Yasuhara K, Hoffman A, Basappa , Metri P, et al.
J Biol Chem . 2024 Oct; 300(12):107916. PMID: 39454959
Growing evidence supports pathogenic roles for chronically elevated hyaluronidase activity in numerous conditions. Elevated expression of one such hyaluronidase, the Cell Migration Inducing and hyaluronan binding Protein (CEMIP), has been...
2.
Riddle A, Srivastava T, Wang K, Tellez E, ONeill H, Gong X, et al.
bioRxiv . 2024 Jul; PMID: 39071376
Objective: Although nearly half of preterm survivors display persistent neurobehavioral dysfunction including memory impairment without overt gray matter injury, the underlying mechanisms of neuronal or glial dysfunction, and their relationship...
3.
Srivastava T, Nguyen H, Haden G, Diba P, Sowa S, LaNguyen N, et al.
J Neurosci . 2024 Apr; 44(21). PMID: 38569926
Proteoglycans containing link domains modify the extracellular matrix (ECM) to regulate cellular homeostasis and can also sensitize tissues/organs to injury and stress. Hypoxic-ischemic (H-I) injury disrupts cellular homeostasis by activating...
4.
Bagi Z, Sherman L, Back S
Aging (Albany NY) . 2023 Aug; 15(16):7860-7862. PMID: 37606973
No abstract available.
5.
Adeniyi P, Gong X, MacGregor E, Degener-OBrien K, McClendon E, Garcia M, et al.
Ann Neurol . 2023 Aug; 94(6):1048-1066. PMID: 37605362
Objective: Because the role of white matter (WM) degenerating microglia (DM) in remyelination failure is unclear, we sought to define the core features of this novel population of aging human...
6.
Adeniyi P, Fopiano K, Banine F, Garcia M, Gong X, Keene C, et al.
ASN Neuro . 2022 Sep; 14:17590914221123138. PMID: 36164936
A major limitation of mechanistic studies in aging brains is the lack of routine methods to robustly visualize and discriminate the cellular distribution of tissue antigens using fluorescent immunohistochemical multi-labeling...
7.
Bagi Z, Kroenke C, Fopiano K, Tian Y, Filosa J, Sherman L, et al.
Geroscience . 2022 May; 44(4):1-14. PMID: 35612774
Patients with Alzheimer's disease (AD) often have cerebral white matter (WM) hyperintensities on MRI and microinfarcts of presumed microvascular origin pathologically. Here, we determined if vasodilator dysfunction of WM-penetrating arterioles...
8.
Vannucci S, Back S
Dev Neurosci . 2022 Mar; 44(4-5):186-193. PMID: 35263745
Perinatal hypoxic-ischemic (HI) brain damage has long been a major cause of acute mortality and chronic neurological morbidity in infants and children. Experimental animal models are essential to gain insights...
9.
Srivastava T, Sherman L, Back S
Neurochem Res . 2019 Sep; 45(3):672-683. PMID: 31542857
Although the extra cellular matrix (ECM) comprises a major proportion of the CNS parenchyma, new roles for the ECM in regeneration and repair responses to CNS injury have only recently...
10.
Su W, Matsumoto S, Banine F, Srivastava T, Dean J, Foster S, et al.
Glia . 2019 Sep; 68(2):263-279. PMID: 31490574
Myelination delay and remyelination failure following insults to the central nervous system (CNS) impede axonal conduction and lead to motor, sensory and cognitive impairments. Both myelination and remyelination are often...