Stephanie Slupek
Overview
Explore the profile of Stephanie Slupek including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
146
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Recent Articles
1.
Coutte L, Antoine R, Slupek S, Locht C
mSystems
. 2024 Mar;
9(4):e0095123.
PMID: 38470037
The regulation of virulence is mediated by the two-component system BvgA/S, which activates the transcription of virulence-activated genes (s). In the avirulent phase, the s are not expressed, but instead,...
2.
Khiter F, Kherrouche Z, Dubois V, Slupek S, Petit E, Debrie A, et al.
Front Immunol
. 2023 Oct;
14:1254276.
PMID: 37841236
is a highly contagious respiratory pathogen responsible for whooping-cough or pertussis. Despite high vaccination coverage worldwide, this gram-negative bacterium continues to spread among the population. is transmitted by aerosol droplets...
3.
Faion L, Djaout K, Pintiala C, Piveteau C, Leroux F, Biela A, et al.
Pharmaceuticals (Basel)
. 2023 Mar;
16(3).
PMID: 36986435
, the pathogen that causes tuberculosis, is responsible for the death of 1.5 million people each year and the number of bacteria resistant to the standard regimen is constantly increasing....
4.
Roy G, Antoine R, Schwartz A, Slupek S, Rivera-Millot A, Boudvillain M, et al.
mBio
. 2022 Jul;
13(4):e0091222.
PMID: 35862763
Copper is essential to most living beings but also highly toxic and as such is an important player at the host-pathogen interface. Bacteria have thus developed homeostatic mechanisms to tightly...
5.
Flipo M, Frita R, Bourotte M, Martinez-Martinez M, Boesche M, Boyle G, et al.
Sci Transl Med
. 2022 May;
14(643):eaaz6280.
PMID: 35507672
The sensitivity of , the pathogen that causes tuberculosis (TB), to antibiotic prodrugs is dependent on the efficacy of the activation process that transforms the prodrugs into their active antibacterial...
6.
Rivera-Millot A, Slupek S, Chatagnon J, Roy G, Saliou J, Billon G, et al.
Commun Biol
. 2021 Jan;
4(1):46.
PMID: 33420409
Copper is both essential and toxic to living beings, which tightly controls its intracellular concentration. At the host-pathogen interface, copper is used by phagocytic cells to kill invading microorganisms. We...
7.
Coutte L, Antoine R, Slupek S, Solans L, Derop J, Bonnefond A, et al.
mSystems
. 2020 May;
5(3).
PMID: 32430408
regulates the production of its virulence factors by the two-component system BvgAS. In the virulence phase, BvgS phosphorylates BvgA, which then activates the transcription of virulence-activated genes (s). In the...
8.
Raze D, Segers J, Mille C, Slupek S, Lecher S, Coutte L, et al.
Mol Microbiol
. 2019 Oct;
113(1):52-67.
PMID: 31587365
The heparin-binding hemagglutinin (HBHA) is a multifunctional protein involved in adherence of Mycobacterium tuberculosis to non-phagocytic cells and in the formation of intracytosolic lipid inclusions. We demonstrate that the expression...
9.
Lesne E, Coutte L, Solans L, Slupek S, Debrie A, Dhennin V, et al.
PLoS One
. 2018 Oct;
13(10):e0204861.
PMID: 30307950
The whooping cough agent Bordetella pertussis coordinately regulates the expression of its virulence factors with the two-component system BvgAS. In laboratory conditions, specific chemical modulators are used to trigger phenotypic...
10.
Amman F, DHalluin A, Antoine R, Huot L, Bibova I, Keidel K, et al.
RNA Biol
. 2018 Apr;
15(7):967-975.
PMID: 29683387
Bordetella pertussis is the causative agent of whooping cough, a respiratory disease still considered as a major public health threat and for which recent re-emergence has been observed. Constant reshuffling...