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Stephanie Schiefer

Explore the profile of Stephanie Schiefer including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Weirich F, Gremer L, Mirecka E, Schiefer S, Hoyer W, Heise H
PLoS One . 2016 Sep; 11(9):e0161243. PMID: 27607147
Amyloid deposits formed from islet amyloid polypeptide (IAPP) are a hallmark of type 2 diabetes mellitus and are known to be cytotoxic to pancreatic β-cells. The molecular structure of the...
2.
Wordehoff M, Bannach O, Shaykhalishahi H, Kulawik A, Schiefer S, Willbold D, et al.
J Mol Biol . 2015 Feb; 427(6 Pt B):1428-1435. PMID: 25659910
Neurodegenerative disorders associated with protein misfolding are fatal diseases that are caused by fibrillation of endogenous proteins such as α-synuclein (α-syn) in Parkinson's disease (PD) or amyloid-β in Alzheimer's disease....
3.
Mirecka E, Gremer L, Schiefer S, Oesterhelt F, Stoldt M, Willbold D, et al.
J Biotechnol . 2014 Jun; 191:221-7. PMID: 24928165
Human islet amyloid polypeptide (IAPP) is the major component of pancreatic amyloid deposits in type 2 diabetes. The structural conversion of IAPP from a monomeric state into amyloid assemblies is...