Stephanie Joaquim
Overview
Explore the profile of Stephanie Joaquim including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
129
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0
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Recent Articles
1.
Kim-Muller J, Song L, Paulhus B, Pashos E, Li X, Rinaldi A, et al.
Cell Rep
. 2023 Jan;
42(1):111947.
PMID: 36640326
Cancer cachexia is a disorder characterized by involuntary weight loss and impaired physical performance. Decline in physical performance of patients with cachexia is associated with poor quality of life, and...
2.
Breen D, Jagarlapudi S, Patel A, Zou C, Joaquim S, Li X, et al.
iScience
. 2021 Jun;
24(6):102554.
PMID: 34189431
Growth differentiation factor 15 (GDF15) causes anorexia and weight loss in animal models, and higher circulating levels are associated with cachexia and reduced survival in cancer and other chronic diseases...
3.
Cimino I, Kim H, Tung Y, Pedersen K, Rimmington D, Tadross J, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(27).
PMID: 34187898
An acute increase in the circulating concentration of glucocorticoid hormones is essential for the survival of severe somatic stresses. Circulating concentrations of GDF15, a hormone that acts in the brain...
4.
Breen D, Kim H, Bennett D, Calle R, Collins S, Esquejo R, et al.
Cell Metab
. 2020 Nov;
32(6):938-950.e6.
PMID: 33207247
Platinum-based cancer therapy is restricted by dose-limiting side effects and is associated with elevation of growth differentiation factor 15 (GDF-15). But whether this elevation contributes to such side effects has...
5.
Bernardo B, Joaquim S, Garren J, Boucher M, Houle C, LaCarubba B, et al.
J Cachexia Sarcopenia Muscle
. 2020 Sep;
11(6):1813-1829.
PMID: 32924335
Background: Cancer cachexia is a complex metabolic disease with unmet medical need. Although many rodent models are available, none are identical to the human disease. Therefore, the development of new...