Stephanie Hugues
Overview
Explore the profile of Stephanie Hugues including associated specialties, affiliations and a list of published articles.
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66
Citations
3649
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Recent Articles
1.
Sun M, Angelillo J, Hugues S
J Exp Med
. 2025 Feb;
222(3).
PMID: 39969537
Although lymphatic vessels (LVs) are present in many tumors, their importance in cancer has long been underestimated. In contrast to the well-studied tumor-associated blood vessels, LVs were previously considered to...
2.
Sun M, Garnier L, Chevalier R, Roumain M, Wang C, Angelillo J, et al.
Nat Commun
. 2025 Jan;
16(1):1217.
PMID: 39890772
In melanoma, lymphangiogenesis correlates with metastasis and poor prognosis and promotes immunosuppression. However, it also potentiates immunotherapy by supporting immune cell trafficking. We show in a lymphangiogenic murine melanoma that...
3.
Chizzolini C, Guery J, Noulet F, Gruaz L, Cenac C, Frasca L, et al.
J Transl Autoimmun
. 2024 Oct;
9:100252.
PMID: 39444662
Objective: B cells play a major role in the development and maintenance of systemic lupus erythematosus (SLE). Double negative (DN) B cells defined by the lack of surface expression of...
4.
5.
Wang C, Zeng Q, Gul Z, Wang S, Pick R, Cheng P, et al.
Cell
. 2024 May;
187(11):2690-2702.e17.
PMID: 38723627
The quality and quantity of tumor-infiltrating lymphocytes, particularly CD8 T cells, are important parameters for the control of tumor growth and response to immunotherapy. Here, we show in murine and...
6.
Kallal N, Hugues S, Garnier L
Eur J Immunol
. 2024 Feb;
54(4):e2350482.
PMID: 38335316
The CNS has traditionally been considered an immune-privileged organ, but recent studies have identified a plethora of immune cells in the choroid plexus, meninges, perivascular spaces, and cribriform plate. Although...
7.
Zimmermannova O, Ferreira A, Ascic E, Velasco Santiago M, Kurochkin I, Hansen M, et al.
Sci Immunol
. 2023 Jul;
8(85):eadd4817.
PMID: 37418548
Decreased antigen presentation contributes to the ability of cancer cells to evade the immune system. We used the minimal gene regulatory network of type 1 conventional dendritic cells (cDC1) to...
8.
Ruiz F, Peter B, Rebeaud J, Vigne S, Bressoud V, Roumain M, et al.
EMBO Rep
. 2023 Jan;
24(3):e55328.
PMID: 36715148
The vasculature is a key regulator of leukocyte trafficking into the central nervous system (CNS) during inflammatory diseases including multiple sclerosis (MS). However, the impact of endothelial-derived factors on CNS...
9.
Wang C, Barnoud C, Cenerenti M, Sun M, Caffa I, Kizil B, et al.
Nature
. 2022 Dec;
614(7946):136-143.
PMID: 36470303
The process of cancer immunosurveillance is a mechanism of tumour suppression that can protect the host from cancer development throughout its lifetime. However, it is unknown whether the effectiveness of...
10.
Bonifacio J, Williams N, Garnier L, Hugues S, Schmolke M, Mazel-Sanchez B
J Virol
. 2022 Oct;
96(20):e0087122.
PMID: 36190240
Together with inactivated influenza vaccines (IIV), live attenuated influenza vaccines (LAIV) are an important tool to prevent influenza A virus (IAV) illnesses in patients. LAIVs present the advantages to have...