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Stephanie Holst

Explore the profile of Stephanie Holst including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 859
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Recent Articles
1.
Zhang J, Zhang Z, Holst S, Blochl C, Madunic K, Wuhrer M, et al.
J Biol Chem . 2022 Feb; 298(3):101717. PMID: 35151689
Pancreatic ductal adenocarcinoma (PDAC) is characterized by poor prognosis and high mortality. Transforming growth factor-β (TGF-β) plays a key role in PDAC tumor progression, which is often associated with aberrant...
2.
de Jonge H, Cruz M, Holst S
Nature . 2021 Nov; 599(7885):372. PMID: 34785800
No abstract available.
3.
Boyaval F, Van Zeijl R, Dalebout H, Holst S, van Pelt G, Farina-Sarasqueta A, et al.
Mol Cell Proteomics . 2021 Feb; 20:100057. PMID: 33581319
The choice for adjuvant chemotherapy in stage II colorectal cancer is controversial as many patients are cured by surgery alone and it is difficult to identify patients with high risk...
4.
Jongsma M, de Waard A, Raaben M, Zhang T, Cabukusta B, Platzer R, et al.
Immunity . 2021 Feb; 54(2):387. PMID: 33567263
No abstract available.
5.
Jongsma M, de Waard A, Raaben M, Zhang T, Cabukusta B, Platzer R, et al.
Immunity . 2020 Dec; 54(1):132-150.e9. PMID: 33271119
HLA class I (HLA-I) glycoproteins drive immune responses by presenting antigens to cognate CD8 T cells. This process is often hijacked by tumors and pathogens for immune evasion. Because options...
6.
Westhrin M, Kovcic V, Zhang Z, Moen S, Nedal T, Bondt A, et al.
Blood . 2020 Jun; 136(23):2656-2666. PMID: 32575115
Most patients with multiple myeloma develop a severe osteolytic bone disease. The myeloma cells secrete immunoglobulins, and the presence of monoclonal immunoglobulins in the patient's sera is an important diagnostic...
7.
Zhang T, Madunic K, Holst S, Zhang J, Jin C, Ten Dijke P, et al.
Mol Omics . 2020 Apr; 16(4):355-363. PMID: 32281997
Changes in glycosylation signatures of cells have been associated with pathological processes in cancer as well as infectious and autoimmune diseases. The current protocols for comprehensive analysis of N-glycomics and...
8.
Madunic K, Zhang T, Mayboroda O, Holst S, Stavenhagen K, Jin C, et al.
Cell Mol Life Sci . 2020 Apr; 78(1):337-350. PMID: 32236654
Alterations in protein glycosylation in colorectal cancer (CRC) have been extensively studied using cell lines as models. However, little is known about their O-glycome and the differences in glycan biosynthesis...
9.
Muller Y, Hage S, Alkhashrom S, Hollriegl T, Weigert S, Dolles S, et al.
J Biol Chem . 2020 Jan; 295(10):3189-3201. PMID: 31980459
Herpesviruses uniquely express two essential nuclear egress-regulating proteins forming a heterodimeric basic structure of the nuclear egress complex (core NEC). These core NECs serve as a hexameric lattice-structured platform for...
10.
Holst S, Wilding J, Koprowska K, Rombouts Y, Wuhrer M
Cells . 2019 Mar; 8(3). PMID: 30909444
The caudal-related homeobox protein 1 (CDX1) is a transcription factor, which is important in the development, differentiation, and homeostasis of the gut. Although the involvement of CDX genes in the...