» Authors » Stephanie C Weber

Stephanie C Weber

Explore the profile of Stephanie C Weber including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 21
Citations 1337
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
11.
A P, Weber S
Noncoding RNA . 2019 Nov; 5(4). PMID: 31683819
Enclosed by two membranes, the nucleus itself is comprised of various membraneless compartments, including nuclear bodies and chromatin domains. These compartments play an important though still poorly understood role in...
12.
Weber S
Curr Opin Cell Biol . 2017 Mar; 46:62-71. PMID: 28343140
Concomitant with packaging the genome, the cell nucleus must also spatially organize the nucleoplasm. This complex mixture of proteins and nucleic acids partitions into a variety of phase-separated, membraneless organelles...
13.
Uppaluri S, Weber S, Brangwynne C
Cell Rep . 2016 Oct; 17(2):345-352. PMID: 27705784
Multicellular organisms must regulate their growth across the diverse length scales of biological organization, but how this growth is controlled from organelle to body, while coordinating interdependent functions at each...
14.
Berry J, Weber S, Vaidya N, Haataja M, Brangwynne C
Proc Natl Acad Sci U S A . 2015 Sep; 112(38):E5237-45. PMID: 26351690
Nuclear bodies are RNA and protein-rich, membraneless organelles that play important roles in gene regulation. The largest and most well-known nuclear body is the nucleolus, an organelle whose primary function...
15.
Weber S, Brangwynne C
Curr Biol . 2015 Feb; 25(5):641-6. PMID: 25702583
Just as organ size typically increases with body size, the size of intracellular structures changes as cells grow and divide. Indeed, many organelles, such as the nucleus [1, 2], mitochondria...
16.
Weber S, Thompson M, Moerner W, Spakowitz A, Theriot J
Biophys J . 2012 Jun; 102(11):2443-50. PMID: 22713559
Single particle tracking is a powerful technique for investigating the dynamic behavior of biological molecules. However, many of the analytical tools are prone to generate results that can lead to...
17.
Weber S, Brangwynne C
Cell . 2012 Jun; 149(6):1188-91. PMID: 22682242
Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular details of their assembly are poorly understood. Several recent papers identify structural features that drive granule assembly,...
18.
Weber S, Spakowitz A, Theriot J
Proc Natl Acad Sci U S A . 2012 Apr; 109(19):7338-43. PMID: 22517744
Chromosomal loci jiggle in place between segregation events in prokaryotic cells and during interphase in eukaryotic nuclei. This motion seems random and is often attributed to brownian motion. However, we...
19.
Weber S, Spakowitz A, Theriot J
Phys Rev Lett . 2010 Sep; 104(23):238102. PMID: 20867274
Tracking of fluorescently labeled chromosomal loci in live bacterial cells reveals a robust scaling of the mean square displacement (MSD) as τ(0.39). We propose that the observed motion arises from...
20.
Weber S, Theriot J, Spakowitz A
Phys Rev E Stat Nonlin Soft Matter Phys . 2010 Sep; 82(1 Pt 1):011913. PMID: 20866654
We use Brownian dynamics simulations and analytical theory to investigate the physical principles underlying subdiffusive motion of a polymer. Specifically, we examine the consequences of confinement, self-interaction, viscoelasticity, and random...