Stephanie A Schroer
Overview
Explore the profile of Stephanie A Schroer including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
756
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Recent Articles
1.
Luk C, Chan C, Chiu F, Shi S, Misra P, Li Y, et al.
Diabetes
. 2023 Sep;
72(12):1751-1765.
PMID: 37699387
Article Highlights: Caspase 8 is increased in adipocytes from mice and humans with obesity and insulin resistance. Knockdown of caspase 8 in adipocytes protects mice from glucose intolerance and weight...
2.
Emoto T, Lu J, Sivasubramaniyam T, Maan H, Khan A, Abow A, et al.
Immunity
. 2022 May;
55(5):862-878.e8.
PMID: 35508166
Macrophage colony stimulating factor-1 (CSF-1) plays a critical role in maintaining myeloid lineage cells. However, congenital global deficiency of CSF-1 (Csf1) causes severe musculoskeletal defects that may indirectly affect hematopoiesis....
3.
Jiang Z, Li H, Schroer S, Voisin V, Ju Y, Pacal M, et al.
EMBO J
. 2022 Jan;
41(4):e106825.
PMID: 35023164
Despite extensive analysis of pRB phosphorylation in vitro, how this modification influences development and homeostasis in vivo is unclear. Here, we show that homozygous Rb and Rb knock-in mice, in...
4.
Dodington D, Yumol J, Yang J, Pollock-Tahiri E, Sivasubramaniyam T, Sacco S, et al.
JCI Insight
. 2021 Mar;
6(5).
PMID: 33682794
Osteoclasts are specialized cells of the hematopoietic lineage that are responsible for bone resorption and play a critical role in musculoskeletal disease. JAK2 is a key mediator of cytokine and...
5.
Sivasubramaniyam T, Yang J, Pollock E, Chon J, Schroer S, Li Y, et al.
Endocrinology
. 2021 Mar;
162(5).
PMID: 33647942
Atherosclerosis is the leading cause of cardiovascular disease (CVD), with distinct sex-specific pathogenic mechanisms that are poorly understood. Aging, a major independent risk factor for atherosclerosis, correlates with a decline...
6.
Sivasubramaniyam T, Yang J, Cheng H, Zyla A, Li A, Besla R, et al.
Sci Rep
. 2021 Feb;
11(1):4723.
PMID: 33633277
Inflammation is a key contributor to atherosclerosis with macrophages playing a pivotal role through the induction of oxidative stress and cytokine/chemokine secretion. DJ1, an anti-oxidant protein, has shown to paradoxically...
7.
Lino M, Ngai D, Liu A, Mohabeer A, Harper C, Caruso L, et al.
Mol Metab
. 2020 May;
39:101006.
PMID: 32360427
Objective: Discoidin domain receptor 1 (DDR1) is a collagen binding receptor tyrosine kinase implicated in atherosclerosis, fibrosis, and cancer. Our previous research showed that DDR1 could regulate smooth muscle cell...
8.
Desai H, Sivasubramaniyam T, Revelo X, Schroer S, Luk C, Rikkala P, et al.
Sci Rep
. 2017 Aug;
7(1):7653.
PMID: 28794431
During obesity, macrophages can infiltrate metabolic tissues, and contribute to chronic low-grade inflammation, and mediate insulin resistance and diabetes. Recent studies have elucidated the metabolic role of JAK2, a key...
9.
Sivasubramaniyam T, Schroer S, Li A, Luk C, Shi S, Besla R, et al.
JCI Insight
. 2017 Jul;
2(14).
PMID: 28724798
Atherosclerosis is considered both a metabolic and inflammatory disease; however, the specific tissue and signaling molecules that instigate and propagate this disease remain unclear. The liver is a central site...
10.
Ghazarian M, Revelo X, Nohr M, Luck H, Zeng K, Lei H, et al.
Sci Immunol
. 2017 Jun;
2(10).
PMID: 28567448
Obesity-related insulin resistance is driven by low-grade chronic inflammation of metabolic tissues. In the liver, non-alcoholic fatty liver disease (NAFLD) is associated with hepatic insulin resistance and systemic glucose dysregulation....