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Stephanie A Fiedler

Explore the profile of Stephanie A Fiedler including associated specialties, affiliations and a list of published articles. Areas
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Citations 41
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Recent Articles
1.
Dagnew T, Tseng C, Yoo C, Makary M, Goodheart A, Striar R, et al.
iScience . 2024 Jul; 27(7):110159. PMID: 39021792
Alcohol use disorder (AUD) is a disorder of clinical and public health significance requiring novel and improved therapeutic solutions. Both environmental and genetic factors play a significant role in its...
2.
Xu Y, Wang C, Wey H, Liang Y, Chen Z, Choi S, et al.
J Exp Med . 2020 Sep; 217(12). PMID: 32936886
The pathogenesis of Alzheimer's disease (AD) is primarily driven by brain accumulation of the amyloid-β-42 (Aβ42) peptide generated from the amyloid-β precursor protein (APP) via cleavages by β- and γ-secretase....
3.
Chen Z, Wang X, Yang X, Xu Y, Yang Y, Wang H, et al.
Eur J Nucl Med Mol Imaging . 2020 Jun; 48(1):53-66. PMID: 32592040
Purpose: Castration-resistant prostate cancer (CRPC) is the most common cause of death in men. The effectiveness of HDAC inhibitors has been demonstrated by preclinical models, but not in clinical studies,...
4.
Bai P, Bai S, Placzek M, Lu X, Fiedler S, Ntaganda B, et al.
Molecules . 2020 Feb; 25(5). PMID: 32106419
The orexin receptor (OX) is critically involved in motivation and sleep-wake regulation and holds promising therapeutic potential in various mood disorders. To further investigate the role of orexin receptors (OXRs)...
5.
Lan Y, Bai P, Chen Z, Neelamegam R, Placzek M, Wang H, et al.
Acta Pharm Sin B . 2019 Dec; 9(6):1204-1215. PMID: 31867166
The sigma-1 receptor ( R) is a unique intracellular protein. R plays a major role in various pathological conditions in the central nervous system (CNS), implicated in several neuropsychiatric disorders....