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Stephane Le Crom

Explore the profile of Stephane Le Crom including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 2193
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Recent Articles
1.
Nashed S, El Barbry H, Benchouaia M, Dijoux-Marechal A, Delaveau T, Ruiz-Gutierrez N, et al.
PLoS Genet . 2023 Aug; 19(8):e1010848. PMID: 37585488
N-terminal ends of polypeptides are critical for the selective co-translational recruitment of N-terminal modification enzymes. However, it is unknown whether specific N-terminal signatures differentially regulate protein fate according to their...
2.
Mazare N, Oudart M, Moulard J, Cheung G, Tortuyaux R, Mailly P, et al.
Cell Rep . 2020 Aug; 32(8):108076. PMID: 32846133
Local translation is a conserved mechanism conferring cells the ability to quickly respond to local stimuli. In the brain, it has been recently reported in astrocytes, whose fine processes contact...
3.
Benchouaia M, Ripoche H, Sissoko M, Thiebaut A, Merhej J, Delaveau T, et al.
Front Microbiol . 2018 Dec; 9:2689. PMID: 30505294
In this work, we used comparative transcriptomics to identify regulatory outliers (ROs) in the human pathogen . ROs are genes that have very different expression patterns compared to their orthologs...
4.
Chasseigneaux S, Moraca Y, Cochois-Guegan V, Boulay A, Gilbert A, Le Crom S, et al.
Sci Rep . 2018 Aug; 8(1):12272. PMID: 30116021
Brain mural cells form a heterogeneous family which significantly contributes to the maintenance of the blood-brain barrier and regulation of the cerebral blood flow. Current procedures to isolate them cannot...
5.
Dardalhon-Cumenal D, Deraze J, Dupont C, Ribeiro V, Coleno-Costes A, Pouch J, et al.
PLoS Genet . 2018 Jul; 14(7):e1007498. PMID: 29995890
In Drosophila, ubiquitous expression of a short Cyclin G isoform generates extreme developmental noise estimated by fluctuating asymmetry (FA), providing a model to tackle developmental stability. This transcriptional cyclin interacts...
6.
Bataille A, Galichon P, Chelghoum N, Mohand Oumoussa B, Ziliotis M, Sadia I, et al.
Cell Physiol Biochem . 2018 Jun; 47(4):1338-1351. PMID: 29929186
Background/aims: Fatty acid oxidation (FAO), the main source of energy produced by tubular epithelial cells in the kidney, was found to be defective in tubulo-interstitial samples dissected out in kidney...
7.
Meng A, Marchet C, Corre E, Peterlongo P, Alberti A, Da Silva C, et al.
Microbiome . 2018 Jun; 6(1):105. PMID: 29885666
Background: Study of meta-transcriptomic datasets involving non-model organisms represents bioinformatic challenges. The production of chimeric sequences and our inability to distinguish the taxonomic origins of the sequences produced are inherent...
8.
Meng A, Corre E, Probert I, Gutierrez-Rodriguez A, Siano R, Annamale A, et al.
Mol Ecol . 2018 Apr; 27(10):2365-2380. PMID: 29624751
Dinoflagellates are one of the most abundant and functionally diverse groups of eukaryotes. Despite an overall scarcity of genomic information for dinoflagellates, constantly emerging high-throughput sequencing resources can be used...
9.
Boulay A, Gilbert A, Oliveira Moreira V, Blugeon C, Perrin S, Pouch J, et al.
Brain Sci . 2018 Mar; 8(4). PMID: 29565275
Astrocytes are the most abundant glial cells of the central nervous system and have recently been recognized as crucial in the regulation of brain immunity. In most neuropathological conditions, astrocytes...
10.
Abdollahi N, Albani A, Anthony E, Baud A, Cardon M, Clerc R, et al.
PLoS Comput Biol . 2018 Mar; 14(3):e1005992. PMID: 29543809
We present a new educational initiative called Meet-U that aims to train students for collaborative work in computational biology and to bridge the gap between education and research. Meet-U mimics...