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Stephane Coulon

Explore the profile of Stephane Coulon including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 810
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Recent Articles
1.
Kochman R, Ba I, Yates M, Pirabakaran V, Gourmelon F, Churikov D, et al.
Genes Dev . 2024 Sep; 38(15-16):755-771. PMID: 39231615
Premature telomere shortening or telomere instability is associated with a group of rare and heterogeneous diseases collectively known as telomere biology disorders (TBDs). Here we identified two unrelated individuals with...
2.
Colin L, Reyes C, Berthezene J, Maestroni L, Modolo L, Toselli E, et al.
Elife . 2023 Nov; 12. PMID: 37988290
The localization of condensin along chromosomes is crucial for their accurate segregation in anaphase. Condensin is enriched at telomeres but how and for what purpose had remained elusive. Here, we...
3.
Carvalho Borges P, Bouabboune C, Escandell J, Matmati S, Coulon S, Ferreira M
Nucleic Acids Res . 2023 Nov; 51(22):12325-12336. PMID: 37953281
Telomeres are nucleoprotein complexes that protect the chromosome-ends from eliciting DNA repair while ensuring their complete duplication. Pot1 is a subunit of telomere capping complex that binds to the G-rich...
4.
Vaurs M, Naiman K, Bouabboune C, Rai S, Ptasinska K, Rives M, et al.
Cell Rep . 2023 May; 42(6):112537. PMID: 37243596
Efficient replication of terminal DNA is crucial to maintain telomere stability. In fission yeast, Taz1 and the Stn1-Ten1 (ST) complex play prominent roles in DNA-ends replication. However, their function remains...
5.
Vaurs M, Audry J, Runge K, Geli V, Coulon S
Nucleic Acids Res . 2022 Nov; 50(20):11682-11695. PMID: 36330920
Telomere elongation is coupled with genome replication, raising the question of the repair of short telomeres in post-mitotic cells. We investigated the fate of a telomere-repeat capped end that mimics...
6.
Giaccherini C, Scaglione S, Coulon S, Dehe P, Gaillard P
PLoS Genet . 2022 Apr; 18(4):e1010165. PMID: 35452455
The Mus81-Eme1 structure-specific endonuclease is crucial for the processing of DNA recombination and late replication intermediates. In fission yeast, stimulation of Mus81-Eme1 in response to DNA damage at the G2/M...
7.
Sharma R, Sahoo S, Honda M, Granger S, Goodings C, Sanchez L, et al.
Blood . 2021 Nov; 139(7):1039-1051. PMID: 34767620
Human telomere biology disorders (TBD)/short telomere syndromes (STS) are heterogeneous disorders caused by inherited loss-of-function mutations in telomere-associated genes. Here, we identify 3 germline heterozygous missense variants in the RPA1...
8.
Maestroni L, Audry J, Luciano P, Coulon S, Geli V, Corda Y
Cell Stress . 2020 Mar; 4(3):48-63. PMID: 32190820
In , the absence of Pif1 helicase induces the instability of G4-containing CEB1 minisatellite during leading strand but not lagging strand replication. We report that RPA and Pif1 cooperate to...
9.
Matmati S, Lambert S, Geli V, Coulon S
Cell Rep . 2020 Mar; 30(10):3312-3322.e3. PMID: 32160539
Telomeres are difficult-to-replicate sites whereby replication itself may threaten telomere integrity. We investigate, in fission yeast, telomere replication dynamics in telomerase-negative cells to unmask problems associated with telomere replication. Two-dimensional...
10.
Berthezene J, Reyes C, Li T, Coulon S, Bernard P, Gachet Y, et al.
Mol Biol Cell . 2020 Feb; 31(9):889-905. PMID: 32101485
In mitosis, while the importance of kinetochore (KT)-microtubule (MT) attachment has been known for many years, increasing evidence suggests that telomere dysfunctions also perturb chromosome segregation by contributing to the...