Stephan Witte
Overview
Explore the profile of Stephan Witte including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
457
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Llitjos J, Carrol E, Osuchowski M, Bonneville M, Scicluna B, Payen D, et al.
Crit Care
. 2024 Jul;
28(1):238.
PMID: 39003476
Implementation of biomarkers in sepsis and septic shock in emergency situations, remains highly challenging. This viewpoint arose from a public-private 3-day workshop aiming to facilitate the transition of sepsis biomarkers...
2.
Francois B, Lambden S, Gibot S, Derive M, Olivier A, Cuvier V, et al.
BMJ Open
. 2021 Jul;
11(7):e042921.
PMID: 34233965
Introduction: Septic shock is the subgroup of patients with sepsis, which presents as vasopressor dependence, an elevated blood lactate concentration and is associated with a mortality of at least 30%....
3.
Francois B, Wittebole X, Ferrer R, Mira J, Dugernier T, Gibot S, et al.
Intensive Care Med
. 2020 May;
46(7):1425-1437.
PMID: 32468087
Purpose: Nangibotide is a specific TREM-1 inhibitor that tempered deleterious host-pathogens interactions, restored vascular function, and improved survival, in animal septic shock models. This study evaluated the safety and pharmacokinetics...
4.
Pandya P, Pasvolsky R, Babichev Y, Braiman A, Witte S, Altman A, et al.
Biochem Biophys Res Commun
. 2019 Jan;
509(2):469-475.
PMID: 30595380
PICOT is a ubiquitous protein that has no functional redundant ortholog and is critical for mouse embryonic development. It is involved in the regulation of signal transduction in T lymphocytes...
5.
Cuvier V, Lorch U, Witte S, Olivier A, Gibot S, Delor I, et al.
Br J Clin Pharmacol
. 2018 Jun;
84(10):2270-2279.
PMID: 29885068
Aims: The peptide nangibotide is the first clinical-stage agent targeting the immunoreceptor TREM-1 (triggering receptor expressed on myeloid cells-1) and is being investigated as a novel therapy for acute inflammatory...
6.
Heubi J, Schaeffer D, Ahrens R, Sollo N, Strausbaugh S, Graff G, et al.
J Pediatr
. 2016 Jun;
176:156-161.e1.
PMID: 27297209
Objective: To evaluate the safety and efficacy of a novel microbial lipase (NM-BL) in a liquid formulation for the treatment of exocrine pancreatic insufficiency (EPI) in patients with cystic fibrosis...
7.
Buttgereit F, Mehta D, Kirwan J, Szechinski J, Boers M, Alten R, et al.
Ann Rheum Dis
. 2012 May;
72(2):204-10.
PMID: 22562974
Objective: To assess the efficacy and safety of low-dose prednisone chronotherapy using a new modified-release (MR) formulation for the treatment of rheumatoid arthritis (RA). Methods: In this 12-week, double-blind, placebo-controlled...
8.
Alten R, Doring G, Cutolo M, Gromnica-Ihle E, Witte S, Straub R, et al.
J Rheumatol
. 2010 Aug;
37(10):2025-31.
PMID: 20682671
Objective: To investigate the effects of longterm low-dose chronotherapy with modified-release (MR) prednisone for rheumatoid arthritis (RA) on the hypothalamus-pituitary-adrenal (HPA) axis as part of the Circadian Administration of Prednisone...
9.
Buttgereit F, Doering G, Schaeffler A, Witte S, Sierakowski S, Gromnica-Ihle E, et al.
Ann Rheum Dis
. 2010 Jun;
69(7):1275-80.
PMID: 20542963
Objective: This 9-month open-label extension of the Circadian Administration of Prednisone in Rheumatoid Arthritis Study (CAPRA 1) investigated the long-term safety and efficacy of prednisone chronotherapy with a novel modified-release...
10.
Buttgereit F, Doering G, Schaeffler A, Witte S, Sierakowski S, Gromnica-Ihle E, et al.
Lancet
. 2008 Jan;
371(9608):205-14.
PMID: 18207016
Background: Circadian rhythms are changed in patients with rheumatoid arthritis. A new modified-release delivery system has been developed which adapts the release of the administered glucocorticoid to the circadian rhythms...