Stephan Saalfeld
Overview
Explore the profile of Stephan Saalfeld including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
30785
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Recent Articles
1.
Benedetti L, Fan R, Weigel A, Moore A, Houlihan P, Kittisopikul M, et al.
Cell
. 2024 Dec;
188(2):484-500.e22.
PMID: 39708809
Neuronal dendrites must relay synaptic inputs over long distances, but the mechanisms by which activity-evoked intracellular signals propagate over macroscopic distances remain unclear. Here, we discovered a system of periodically...
2.
Selzer G, Rueden C, Hiner M, Evans E, Kolb D, Wiedenmann M, et al.
Front Bioinform
. 2024 Oct;
4:1435733.
PMID: 39399098
Decades of iteration on scientific imaging hardware and software has yielded an explosion in not only the size, complexity, and heterogeneity of image datasets but also in the tooling used...
3.
Nern A, Loesche F, Takemura S, Burnett L, Dreher M, Gruntman E, et al.
bioRxiv
. 2024 Apr;
PMID: 38659887
Vision provides animals with detailed information about their surroundings, conveying diverse features such as color, form, and movement across the visual scene. Computing these parallel spatial features requires a large...
4.
Bharathan N, Giang W, Hoffman C, Aaron J, Khuon S, Chew T, et al.
Nat Cell Biol
. 2024 Feb;
26(4):660.
PMID: 38347183
No abstract available.
5.
Popovych S, Macrina T, Kemnitz N, Castro M, Nehoran B, Jia Z, et al.
Nat Commun
. 2024 Jan;
15(1):289.
PMID: 38177169
The reconstruction of neural circuits from serial section electron microscopy (ssEM) images is being accelerated by automatic image segmentation methods. Segmentation accuracy is often limited by the preceding step of...
6.
Moore J, Basurto-Lozada D, Besson S, Bogovic J, Bragantini J, Brown E, et al.
Histochem Cell Biol
. 2023 Jul;
160(3):223-251.
PMID: 37428210
A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across...
7.
Bharathan N, Giang W, Hoffman C, Aaron J, Khuon S, Chew T, et al.
Nat Cell Biol
. 2023 Jun;
25(6):823-835.
PMID: 37291267
The endoplasmic reticulum (ER) forms a dynamic network that contacts other cellular membranes to regulate stress responses, calcium signalling and lipid transfer. Here, using high-resolution volume electron microscopy, we find...
8.
Zhu J, Boivin J, Pang S, Xu C, Lu Z, Saalfeld S, et al.
Curr Biol
. 2023 Jun;
33(12):2491-2503.e4.
PMID: 37285846
Evolution has generated an enormous variety of morphological, physiological, and behavioral traits in animals. How do behaviors evolve in different directions in species equipped with similar neurons and molecular components?...
9.
Moore J, Basurto-Lozada D, Besson S, Bogovic J, Bragantini J, Brown E, et al.
bioRxiv
. 2023 Mar;
PMID: 36865282
A growing community is constructing a next-generation file format (NGFF) for bioimaging to overcome problems of scalability and heterogeneity. Organized by the Open Microscopy Environment (OME), individuals and institutes across...
10.
Sheridan A, Nguyen T, Deb D, Lee W, Saalfeld S, Turaga S, et al.
Nat Methods
. 2022 Dec;
20(2):295-303.
PMID: 36585455
We present an auxiliary learning task for the problem of neuron segmentation in electron microscopy volumes. The auxiliary task consists of the prediction of local shape descriptors (LSDs), which we...