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Stephan Rawer

Explore the profile of Stephan Rawer including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 20
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Recent Articles
1.
Lupu L, Wiegand P, Holdschick D, Mihoc D, Maeser S, Rawer S, et al.
Int J Mol Sci . 2021 Dec; 22(23). PMID: 34884636
Analytical methods for molecular characterization of diagnostic or therapeutic targets have recently gained high interest. This review summarizes the combination of mass spectrometry and surface plasmon resonance (SPR) biosensor analysis...
2.
Maeser S, Petre B, Ion L, Rawer S, Kohlschutter A, Santorelli F, et al.
J Mass Spectrom . 2020 Dec; 56(1):e4675. PMID: 33314470
Neuronal ceroid lipofuscinoses (NCLs) are a group of neurodegenerative diseases predominantly in childhood that are characterized by psychomotor deterioration, epilepsy, and early death of patients. The NCLs analyzed in the...
3.
Wiegand P, Lupu L, Huttmann N, Wack J, Rawer S, Przybylski M, et al.
J Am Soc Mass Spectrom . 2020 Sep; 31(1):109-116. PMID: 32881511
The polypeptide chemokine Interleukin-8 (IL8) plays a crucial role in inflammatory processes in humans. IL8 is involved in chronic inflammatory lung diseases, rheumatoid arthritis, and cancer. Previous studies have shown...
4.
Lupu L, Wiegand P, Huttmann N, Rawer S, Kleinekofort W, Shugureva I, et al.
ChemMedChem . 2019 Dec; 15(4):363-369. PMID: 31825565
C-Met protein is a glycosylated receptor tyrosine kinase of the hepatocyte growth factor (HGF), composed of an α and a β chain. Upon ligand binding, C-Met transmits intracellular signals by...
5.
Baschung Y, Lupu L, Moise A, Glocker M, Rawer S, Lazarev A, et al.
J Am Soc Mass Spectrom . 2018 Jun; 29(9):1881-1891. PMID: 29943080
Affinity mass spectrometry using selective proteolytic excision and extraction combined with MALDI and ESI mass spectrometry has been applied to the identification of epitope binding sites of lactose, GalNac, and...
6.
Moise A, Maeser S, Rawer S, Eggers F, Murphy M, Bornheim J, et al.
J Am Soc Mass Spectrom . 2016 Apr; 27(6):1071-8. PMID: 27112153
Fabry disease (FD) is a rare metabolic disorder of a group of lysosomal storage diseases, caused by deficiency or reduced activity of the enzyme α-galactosidase. Human α-galactosidase A (hαGAL) hydrolyses...
7.
Pipkorn R, Rawer S, Wiessler M, Waldeck W, Koch M, Schrenk H, et al.
Int J Med Sci . 2013 Feb; 10(3):331-7. PMID: 23423830
The personalized medicine, also documented as "individualized medicine", is an effective and therapeutic approach. It is designed to treat the disease of the individual patient whose precise differential gene expression...
8.
Mikolasch A, Hahn V, Manda K, Pump J, Illas N, Gordes D, et al.
Amino Acids . 2010 Feb; 39(3):671-83. PMID: 20143113
In order to design potential biomaterials, we investigated the laccase-catalyzed cross-linking between L-lysine or lysine-containing peptides and dihydroxylated aromatics. L-Lysine is one of the major components of naturally occurring mussel...