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Stephan Ginell

Explore the profile of Stephan Ginell including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 76
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Recent Articles
1.
Cousido-Siah A, Petrova T, Hazemann I, Mitschler A, Ruiz F, Howard E, et al.
Proteins . 2012 Jul; 80(11):2552-61. PMID: 22752989
The relationship between the structures of protein-ligand complexes existing in the crystal and in solution, essential in the case of fragment-based screening by X-ray crystallography (FBS-X), has been often an...
2.
Petrova T, Ginell S, Mitschler A, Kim Y, Lunin V, Joachimiak G, et al.
Acta Crystallogr D Biol Crystallogr . 2010 Oct; 66(Pt 10):1075-91. PMID: 20944241
Overall and site-specific X-ray-induced damage to porcine pancreatic elastase was studied at atomic resolution at temperatures of 100 and 15 K. The experiments confirmed that irradiation causes small movements of...
3.
Petrova T, Lunin V, Ginell S, Hazemann I, Lazarski K, Mitschler A, et al.
J Mol Biol . 2009 Feb; 387(5):1092-105. PMID: 19233199
X-rays interact with biological matter and cause damage. Proteins and other macromolecules are damaged primarily by ionizing X-ray photons and secondarily by reactive radiolytic chemical species. In particular, protein molecules...
4.
Blakeley M, Ruiz F, Cachau R, Hazemann I, Meilleur F, Mitschler A, et al.
Proc Natl Acad Sci U S A . 2008 Feb; 105(6):1844-8. PMID: 18250329
We present results of combined studies of the enzyme human aldose reductase (h-AR, 36 kDa) using single-crystal x-ray data (0.66 A, 100K; 0.80 A, 15K; 1.75 A, 293K), neutron Laue...
5.
Petrova T, Ginell S, Mitschler A, Hazemann I, Schneider T, Cousido A, et al.
Acta Crystallogr D Biol Crystallogr . 2006 Dec; 62(Pt 12):1535-44. PMID: 17139089
Two X-ray data sets for a complex of human aldose reductase (h-AR) with the inhibitor IDD 594 and the cofactor NADP(+) were collected from two different parts of the same...