Stephan D Bouman
Overview
Explore the profile of Stephan D Bouman including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
219
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0
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Recent Articles
1.
Hvid H, Brand C, Hummelshoj T, Jensen S, Bouman S, Bowler A, et al.
Diabetologia
. 2022 Nov;
66(2):376-389.
PMID: 36404376
Aims/hypothesis: Normalisation of blood glucose in individuals with diabetes is recommended to reduce development of diabetic complications. However, risk of severe hypoglycaemia with intensive insulin therapy is a major obstacle...
2.
Pedersen C, Bouman S, Porsgaard T, Rosenkilde M, Roed N
Physiol Rep
. 2018 Mar;
6(6):e13657.
PMID: 29595915
The current available insulin therapies decrease blood glucose but are associated with the risk of developing hypoglycemia. Glucagon is a counter regulatory hormone and we hypothesize that a fixed ratio...
3.
Kanter J, Kramer F, Barnhart S, Duggan J, Shimizu-Albergine M, Kothari V, et al.
Diabetes
. 2018 Feb;
67(5):946-959.
PMID: 29483182
Cardiovascular disease caused by atherosclerosis is the leading cause of mortality associated with type 2 diabetes and metabolic syndrome. Insulin therapy is often needed to improve glycemic control, but it...
4.
Frikke-Schmidt H, Pedersen T, Fledelius C, Olsen G, Bouman S, Fitch M, et al.
Diabetes
. 2014 Oct;
64(3):1057-66.
PMID: 25315006
In addition to lowering of blood glucose, treatment with insulin also induces lipid synthesis and storage. Patients with type 2 diabetes often suffer from lipid-related comorbidities including dyslipidemia, obesity, and...
5.
Vienberg S, Bouman S, Sorensen H, Stidsen C, Kjeldsen T, Glendorf T, et al.
Biochem J
. 2011 Aug;
440(3):301-8.
PMID: 21851336
The relative expression patterns of the two IR (insulin receptor) isoforms, +/- exon 11 (IR-B/IR-A respectively), are tissue-dependent. Therefore we have developed insulin analogues with different binding affinities for the...
6.
Sickmann H, Waagepetersen H, Schousboe A, Benie A, Bouman S
J Cereb Blood Flow Metab
. 2010 Apr;
30(8):1527-37.
PMID: 20424632
Obesity and type 2 diabetes have reached epidemic proportions; however, scarce information about how these metabolic syndromes influence brain energy and neurotransmitter homeostasis exist. The objective of this study was...
7.
Jessen L, Clegg D, Bouman S
Am J Physiol Regul Integr Comp Physiol
. 2009 Oct;
298(1):R43-50.
PMID: 19864335
Insulin detemir is a novel human insulin analog that does not show the usual propensity for weight gain in diabetic patients. We speculated that this beneficial effect could be due...
8.
Sickmann H, Walls A, Schousboe A, Bouman S, Waagepetersen H
J Neurochem
. 2009 Apr;
109 Suppl 1:80-6.
PMID: 19393012
The involvement of brain glycogen in sustaining neuronal activity has previously been demonstrated. However, to what extent energy derived from glycogen is consumed by astrocytes themselves or is transferred to...
9.
Walls A, Sickmann H, Brown A, Bouman S, Ransom B, Schousboe A, et al.
J Neurochem
. 2008 Jan;
105(4):1462-70.
PMID: 18221367
The pharmacological properties of 1,4-dideoxy-1,4-imino-d-arabinitol (DAB), a potent inhibitor of glycogen phosphorylase and synthase activity in liver preparations, were characterized in different brain tissue preparations as a prerequisite for using...