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Stefano Severi

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Articles 133
Citations 2055
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Recent Articles
11.
Mazhar F, Bartolucci C, Regazzoni F, Paci M, Dede L, Quarteroni A, et al.
J Physiol . 2023 Aug; 602(18):4543-4583. PMID: 37641426
Mechano-electric regulations (MER) play an important role in the maintenance of cardiac performance. Mechano-calcium and mechano-electric feedback (MCF and MEF) pathways adjust the cardiomyocyte contractile force according to mechanical perturbations...
12.
Camporesi M, Bartolucci C, Lei C, Mirams G, de Boer T, Severi S
Comput Cardiol (2010) . 2023 Aug; 40. PMID: 37609071
As drugs can be multichannel blockers it is important to assess their cardiac safety taking into account multiple currents. In silico action potential (AP) models have been proposed for being...
13.
Bocchini M, Tazzari M, Ravaioli S, Piccinini F, Foca F, Tebaldi M, et al.
Front Oncol . 2023 Jun; 13:1136331. PMID: 37287922
Methods: Whole miRNOme NGS profiling was conducted on plasma samples obtained from well-differentiated advanced, metastatic, inoperable G1, G2 and G3 GEP-NET patients enrolled in the non-randomized LUX (NCT02736500) and LUNET...
14.
Altomare C, Bartolucci C, Sala L, Balbi C, Burrello J, Pietrogiovanna N, et al.
Commun Biol . 2023 Mar; 6(1):291. PMID: 36934210
Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (CM) constitute a mixed population of ventricular-, atrial-, nodal-like cells, limiting the reliability for studying chamber-specific disease mechanisms. Previous studies characterised CM phenotype...
15.
DAlessandro N, Falanga M, Masci A, Severi S, Corsi C
Front Cardiovasc Med . 2023 Mar; 10:1067964. PMID: 36891242
Atrial fibrillation (AF) is one of the most investigated arrhythmias since it is associated with a five-fold increase in the risk of strokes. Left atrium dilation and unbalanced and irregular...
16.
Liverani C, Spadazzi C, Ibrahim T, Pieri F, Foca F, Calabrese C, et al.
Front Endocrinol (Lausanne) . 2023 Feb; 13:1045038. PMID: 36743926
Introduction: Neuroendocrine neoplasms (NENs) are a rare group of tumors exceptionally heterogeneous, with clinical presentation ranging from well differentiated more indolent tumors to poorly differentiated very aggressive forms. Both are...
17.
Bongiovanni A, Nicolini S, Ibrahim T, Foca F, Sansovini M, Di Paolo A, et al.
Cancers (Basel) . 2022 Dec; 14(24). PMID: 36551507
Introduction: Neuroendocrine tumors (NETs) are rare malignancies with different prognoses. At least 25% of metastatic patients have functioning neuroendocrine tumors (F-NETs) that secrete bioactive peptides, causing specific debilitating and occasionally...
18.
Campana C, Ricci E, Bartolucci C, Severi S, Sobie E
PLoS Comput Biol . 2022 Nov; 18(11):e1010098. PMID: 36409762
Both experimental and modeling studies have attempted to determine mechanisms by which a small anatomical region, such as the sinoatrial node (SAN), can robustly drive electrical activity in the human...
19.
Ricci E, Bartolucci C, Severi S
Prog Biophys Mol Biol . 2022 Nov; 177:55-79. PMID: 36374743
Since its discovery, the sinoatrial node (SAN) has represented a fascinating and complex matter of research. Despite over a century of discoveries, a full comprehension of pacemaking has still to...
20.
Di Iorio V, Boschi S, Cuni C, Monti M, Severi S, Paganelli G, et al.
Molecules . 2022 Jul; 27(13). PMID: 35807385
Since prostate cancer is the most commonly diagnosed malignancy in men, the theranostic approach has become very attractive since the discovery of urea-based PSMA inhibitors. Different molecules have been synthesized...