Stefanie G Wohl
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Explore the profile of Stefanie G Wohl including associated specialties, affiliations and a list of published articles.
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13
Citations
505
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Recent Articles
1.
Larbi D, Rief A, Kang S, Chen S, Batsuuri K, Fuhrmann S, et al.
Invest Ophthalmol Vis Sci
. 2025 Mar;
66(3):7.
PMID: 40035725
Purpose: The loss of Dicer in Müller glia (MG) results in severe photoreceptor degeneration, as it occurs in retinitis pigmentosa or age-related macular degeneration; however, the sequence of events leading...
2.
Larbi D, Rief A, Kang S, Chen S, Batsuuri K, Fuhrmann S, et al.
bioRxiv
. 2025 Feb;
PMID: 39975262
Purpose: The loss of Dicer in Müller glia (MG) results in severe photoreceptor degeneration as it occurs in retinitis pigmentosa or AMD. However, the sequence of events leading to this...
3.
Kang S, Wohl S
J Vis Exp
. 2022 Apr;
(181).
PMID: 35404354
Müller glia (MG) are the predominant glia in the neural retina and can function as a regenerative source for retinal neurons. In lower vertebrates such as fish, MG-driven regeneration occurs...
4.
Kang S, Larbi D, Andrade M, Reardon S, Reh T, Wohl S
Front Cell Dev Biol
. 2021 Feb;
8:620459.
PMID: 33614628
Müller glia (MG) are the predominant glia in the neural retina and become reactive after injury or in disease. microRNAs (miRNAs) are translational repressors that regulate a variety of processes...
5.
VandenBosch L, Wohl S, Wilken M, Hooper M, Finkbeiner C, Cox K, et al.
Sci Rep
. 2020 Aug;
10(1):13615.
PMID: 32788677
Diseases and damage to the retina lead to losses in retinal neurons and eventual visual impairment. Although the mammalian retina has no inherent regenerative capabilities, fish have robust regeneration from...
6.
Wohl S, Hooper M, Reh T
Development
. 2019 Aug;
146(17).
PMID: 31383796
Müller glial cells (MG) generate retinal progenitor (RPC)-like cells after injury in non-mammalian species, although this does not occur in the mammalian retina. Studies have profiled gene expression in these...
7.
Schultz R, Krug M, Precht M, Wohl S, Witte O, Schmeer C
Sci Rep
. 2018 Mar;
8(1):4846.
PMID: 29555919
Müller cells are critical for retinal function and neuronal survival but can become detrimental in response to retinal ischemia and increased oxidative stress. Elevated oxidative stress increases expression of the...
8.
Wohl S, Jorstad N, Levine E, Reh T
Nat Commun
. 2017 Nov;
8(1):1603.
PMID: 29150673
To better understand the roles of microRNAs in glial function, we used a conditional deletion of Dicer1 (Dicer-CKO) in retinal Müller glia (MG). Dicer1 deletion from the MG leads to...
9.
Jorstad N, Wilken M, Grimes W, Wohl S, VandenBosch L, Yoshimatsu T, et al.
Nature
. 2017 Jul;
548(7665):103-107.
PMID: 28746305
Many retinal diseases lead to the loss of retinal neurons and cause visual impairment. The adult mammalian retina has little capacity for regeneration. By contrast, teleost fish functionally regenerate their...
10.
Wohl S, Reh T
Sci Rep
. 2016 Oct;
6:35423.
PMID: 27739496
The profile of miRNAs in mature glia is not well characterized, and most studies have been done in cultured glia. In order to identify the miRNAs in adult and young...