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Stefania Olla

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Articles 23
Citations 837
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Recent Articles
1.
Floris S, Pintus F, Fais A, Era B, Raho N, Siguri C, et al.
Molecules . 2024 Nov; 29(21). PMID: 39519706
Type 2 diabetes (T2D), characterized by insulin resistance and β-cell dysfunction, requires continuous advancements in management strategies, particularly in controlling postprandial hyperglycemia to prevent complications. Current antidiabetics, which have α-amylase...
2.
Serra R, Rallo V, Steri M, Olla S, Piras M, Marongiu M, et al.
BMC Ophthalmol . 2024 Jul; 24(1):306. PMID: 39044131
Background: Usher syndrome (USH) encompasses a group of disorders characterized by congenital sensorineural hearing loss (SNHL) and retinitis pigmentosa (RP). We described the clinical findings, natural history, and molecular analyses...
3.
Caballero-Oteyza A, Crisponi L, Peng X, Wang H, Mrovecova P, Olla S, et al.
Clin Immunol . 2024 Jun; 265:110292. PMID: 38914362
OTULIN encodes an eponymous linear deubiquitinase (DUB) essential for controlling inflammation as a negative regulator of the canonical NF-κB signaling pathway via the regulation of M1-Ub dynamics. Biallelic loss-of-function (LOF)...
4.
Di Petrillo A, Siguri C, Delogu G, Fais A, Era B, Floris S, et al.
Chem Biol Interact . 2024 Jun; 397:111087. PMID: 38823536
Xanthine oxidase (XO) plays a critical role in purine catabolism, catalyzing the conversion of hypoxanthine to xanthine and xanthine to uric acid, contributing to superoxide anion production. This process is...
5.
Caballero-Oteyza A, Crisponi L, Peng X, Wang H, Mrovecova P, Olla S, et al.
Res Sq . 2024 May; PMID: 38712244
encodes an eponymous linear deubiquitinase (DUB), which through the regulation of M1-Ub dynamics, is essential for controlling inflammation as a negative regulator of the canonical NF-B signaling pathway. Biallelic loss-of-function...
6.
Veroni C, Olla S, Brignone M, Siguri C, Formato A, Marra M, et al.
Biomolecules . 2024 Apr; 14(4). PMID: 38672460
A considerable effort has been spent in the past decades to develop targeted therapies for the treatment of demyelinating diseases, such as multiple sclerosis (MS). Among drugs with free radical...
7.
Olla S, Siguri C, Fais A, Era B, Fantini M, Di Petrillo A
Int J Mol Sci . 2023 Oct; 24(20). PMID: 37895071
Oxidative stress is defined as an imbalance between the production of free radicals and reactive oxygen species (ROS) and the ability of the body to neutralize them by anti-oxidant defense...
8.
Colombo E, Olla S, Minnelli C, Formato A, Veroni C, Corbisiero S, et al.
Molecules . 2023 Oct; 28(19). PMID: 37836771
Edaravone (EDA), an antioxidant drug approved for the treatment of ischemic stroke and amyotrophic lateral sclerosis, was recently proposed as a remyelinating candidate for the treatment of multiple sclerosis. Here,...
9.
Olla S, Steri M, Formato A, Whalen M, Corbisiero S, Agresti C
Pharmaceutics . 2021 Dec; 13(12). PMID: 34959343
In multiple sclerosis (MS), oxidative stress (OS) is implicated in the neurodegenerative processes that occur from the beginning of the disease. Unchecked OS initiates a vicious circle caused by its...
10.
Busonero F, Steri M, Orru V, Sole G, Olla S, Marongiu M, et al.
Br J Haematol . 2020 Nov; 191(5):e124-e128. PMID: 33216977
No abstract available.