Alpha 2.0
Login Register
» Authors » Stefan Toegel

Stefan Toegel

Explore the profile of Stefan Toegel including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 54
Citations 1107
Followers 0
Related Specialties
Biochemistry
Biology
Orthopedics
Top 10 Co-Authors
Reinhard Windhager
Helmut Viernstein
Daniela Weinmann
Hans-Joachim Gabius
Sonja M Walzer
Catharina Chiari
Markus Mitterhauser
Mario Rothbauer
Kurt Kletter
Sabine Andre
Published In
Nucl Med Biol
Front Bioeng Biotechnol
Histochem Cell Biol
BMC Mol Biol
J Orthop Res
Affiliations
Soon will be listed here.
Recent Articles
1.
Improving accuracy in assessing osseointegration in small animal bone using specimen-specific additively-manufactured fixtures based on clinical CT imaging
Pestel M, Alphonsus J, Toegel S, Strassl A, Herold J, Windhager R, et al.
J Mech Behav Biomed Mater . 2025 Feb; 165:106941. PMID: 39983373
Objective: Implant removal is a common method to quantify the level of osseointegration in small animal studies. Due to small implant sizes, precise alignment in removal experiments is crucial to...
2.
The modulating role of uniaxial straining in the IL-1β and TGF-β mediated inflammatory response of human primary ligamentocytes
Heidenberger J, Hangel R, Reihs E, Strauss J, Liskova P, Alphonsus J, et al.
Front Bioeng Biotechnol . 2024 Dec; 12:1469238. PMID: 39720167
Biomechanical (over-)stimulation, in addition to inflammatory and fibrotic stimuli, severely impacts the biology, contributing to the overall chronic nature of desmopathy. A major challenge has been the lack of representative...
3.
The degenerated glenohumeral joint
Toegel S, Martelanz L, Alphonsus J, Hirtler L, Gruebl-Barabas R, Cezanne M, et al.
Bone Joint Res . 2024 Oct; 13(10):596-610. PMID: 39428110
Aims: This study aimed to define the histopathology of degenerated humeral head cartilage and synovial inflammation of the glenohumeral joint in patients with omarthrosis (OmA) and cuff tear arthropathy (CTA)....
4.
Bone-Mimetic Osteon Microtopographies on Poly-ε-Caprolactone Enhance the Osteogenic Potential of Human Mesenchymal Stem Cells
Vostatek M, Verin E, Tamm M, Rothbauer M, Toegel S, Moscato F
Macromol Biosci . 2024 Sep; 25(2):e2400311. PMID: 39234756
The attributes of implant surfaces are pivotal for successful osseointegration. Among surface engineering strategies, microtopography stands out as a promising approach to promote early cellular interactions. This study aims to...
5.
Spheroid trilineage differentiation model of primary mesenchymal stem/stromal cells under hypoxia and serum-free culture conditions
Moldaschl J, Chariyev-Prinz F, Toegel S, Keck M, Hiden U, Egger D, et al.
Front Bioeng Biotechnol . 2024 Aug; 12:1444363. PMID: 39144480
Due to their unique properties, human mesenchymal stem/stromal cells (MSCs) possess tremendous potential in regenerative medicine, particularly in cell-based therapies where the multipotency and immunomodulatory characteristics of MSCs can be...
6.
Medical 3D printing with polyjet technology: effect of material type and printing orientation on printability, surface structure and cytotoxicity
Schneider K, Oberoi G, Unger E, Janjic K, Rohringer S, Heber S, et al.
3D Print Med . 2023 Sep; 9(1):27. PMID: 37768399
Due to its high printing resolution and ability to print multiple materials simultaneously, inkjet technology has found wide application in medicine. However, the biological safety of 3D-printed objects is not...
7.
Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis
Matsuoka K, Bakiri L, Bilban M, Toegel S, Haschemi A, Yuan H, et al.
Ann Rheum Dis . 2023 Jun; 82(9):1227-1239. PMID: 37344157
Objectives: The activator protein-1 (AP-1) transcription factor component c-Fos regulates chondrocyte proliferation and differentiation, but its involvement in osteoarthritis (OA) has not been functionally assessed. Methods: c-Fos expression was evaluated...
8.
Activation of the Mechanosensitive Ion Channels Piezo1 and TRPV4 in Primary Human Healthy and Osteoarthritic Chondrocytes Exhibits Ion Channel Crosstalk and Modulates Gene Expression
Steinecker-Frohnwieser B, Lohberger B, Toegel S, Windhager R, Glanz V, Kratschmann C, et al.
Int J Mol Sci . 2023 May; 24(9). PMID: 37175575
Osteoarthritis (OA) is the most common degenerative joint disease causing pain and functional limitations. Physical activity as a clinically relevant, effective intervention alleviates pain and promotes joint function. In chondrocytes,...
9.
Targeting osteoarthritis-associated galectins and an induced effector class by a ditopic bifunctional reagent: Impact of its glycan part on binding measured in the tissue context
Manning J, Baldoneschi V, Romero-Hernandez L, Pichler K, Caballero G, Andre S, et al.
Bioorg Med Chem . 2022 Nov; 75:117068. PMID: 36327696
Pairing glycans with tissue lectins controls multiple effector pathways in (patho)physiology. A clinically relevant example is the prodegradative activity of galectins-1 and -3 (Gal-1 and -3) in the progression of...
10.
A Progress Report and Roadmap for Microphysiological Systems and Organ-On-A-Chip Technologies to Be More Predictive Models in Human (Knee) Osteoarthritis
Rothbauer M, Reihs E, Fischer A, Windhager R, Jenner F, Toegel S
Front Bioeng Biotechnol . 2022 Jul; 10:886360. PMID: 35782494
Osteoarthritis (OA), a chronic debilitating joint disease affecting hundreds of million people globally, is associated with significant pain and socioeconomic costs. Current treatment modalities are palliative and unable to stop...