Stefan Stahl
Overview
Explore the profile of Stefan Stahl including associated specialties, affiliations and a list of published articles.
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Articles
123
Citations
2093
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Recent Articles
1.
Cheung P, Persson J, Zhang B, Vasylovska S, Lau J, Invast S, et al.
Sci Rep
. 2025 Jan;
15(1):417.
PMID: 39747317
A distinctive feature of both type 1 and type 2 diabetes is the waning of insulin-secreting beta cells in the pancreas. New methods for direct and specific targeting of the...
2.
Zhang J, Rinne S, Yin W, Leitao C, Bjorklund E, Abouzayed A, et al.
ACS Pharmacol Transl Sci
. 2024 Oct;
7(10):3228-3240.
PMID: 39416966
The outcome of clinical trials evaluating drugs targeting the human epidermal growth factor receptor 3 (HER3) has been poor, with primary concerns related to lack of efficacy. HER3 is considered...
3.
Leitao C, Stahl S, Lofblom J
Microb Biotechnol
. 2024 Oct;
17(10):e70033.
PMID: 39403960
Bacterial surface display in combination with fluorescence-activated cell sorting is a versatile and robust system and an interesting alternative approach to phage display for the generation of therapeutic affinity proteins....
4.
Ek M, Nilvebrant J, Nygren P, Stahl S, Lindberg H, Lofblom J
Front Immunol
. 2024 Aug;
15:1437886.
PMID: 39185427
Heterozygous loss-of-function mutations in the gene are a common cause of frontotemporal dementia. Such mutations lead to decreased plasma and cerebrospinal fluid levels of progranulin (PGRN), a neurotrophic factor with...
5.
Parks L, Ek M, Stahl S, Lofblom J
Biochem Biophys Res Commun
. 2024 Jan;
696:149534.
PMID: 38241810
Autotransporters constitute a large family of natural proteins that are essential for delivering many types of proteins and peptides across the outer membrane in Gram-negative bacteria. In biotechnology, autotransporters have...
6.
Cheung P, Thorngren J, Zhang B, Vasylovska S, Lechi F, Persson J, et al.
EJNMMI Res
. 2023 Dec;
13(1):107.
PMID: 38100042
Background: Beta-cell replacement methods such as transplantation of isolated donor islets have been proposed as a curative treatment of type 1 diabetes, but widespread application is challenging due to shortages...
7.
Puuvuori E, Shen Y, Hulsart-Billstrom G, Mitran B, Zhang B, Cheung P, et al.
J Nucl Med
. 2023 Dec;
65(2):294-299.
PMID: 38050119
Rheumatoid arthritis (RA) is the most common inflammatory joint disease, and early diagnosis is key for effective disease management. CD69 is one of the earliest cell surface markers seen at...
8.
Hjelm L, Lindberg H, Stahl S, Lofblom J
Pharmaceuticals (Basel)
. 2023 Jul;
16(7).
PMID: 37513868
The development of biologics for diseases affecting the central nervous system has been less successful compared to other disease areas, in part due to the challenge of delivering drugs to...
9.
Stahl S, Lindberg H, Hjelm L, Lofblom J, Leitao C
Cold Spring Harb Protoc
. 2023 Jul;
2024(11):pdb.top107760.
PMID: 37491082
Affibody molecules are small, robust, and versatile affinity proteins currently being explored for therapeutic, diagnostic, and biotechnological applications. Surface-exposed residues on the affibody scaffold are randomized to create large affibody...
10.
Lofblom J, Hjelm L, Leitao C, Stahl S, Lindberg H
Cold Spring Harb Protoc
. 2023 Jul;
2024(11):pdb.prot108401.
PMID: 37491081
Affibody molecules are small (6-kDa) affinity proteins generated by directed evolution for specific binding to various target molecules. The first step in this workflow involves the generation of an affibody...