Stefan Nierkens
Overview
Explore the profile of Stefan Nierkens including associated specialties, affiliations and a list of published articles.
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Articles
181
Citations
3288
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Recent Articles
1.
Admiraal R, Nierkens S, Bierings M, Belderbos M, Huitema A, Bredius R, et al.
Blood Adv
. 2025 Feb;
PMID: 39983052
Anti-thymocyte globulin (ATG) is used in pediatric allogeneic hematopoietic cell transplantation (HCT) to prevent graft-versus-host-disease (GvHD) and graft failure (GF). Poor or delayed T-cell recovery, associated with increased mortality, is...
2.
Golwala Z, Spiridou Goncalves H, Moirangthem R, Evans G, Lizot S, de Koning C, et al.
Clin Immunol
. 2025 Feb;
274:110453.
PMID: 39965724
Persistent selective T-lymphocytopenia is found both in SCID and congenital athymia. Without molecular diagnosis, it is challenging to determine whether HCT or thymus transplantation ought to be performed. Ex vivo...
3.
Lachmann G, Heeren P, Schuster F, Nyvlt P, Spies C, Feinkohl I, et al.
J Intern Med
. 2025 Jan;
297(3):312-327.
PMID: 39868852
Background: Five fulfilled hemophagocytic lymphohistiocytosis (HLH)-2004 criteria, and the HScore are widely used and recommended by international expert consensus to diagnose secondary HLH. Both diagnostic scores have never been validated...
4.
Muskens K, Wieringa N, van Bergen M, Bense J, Te Pas B, de Pagter A, et al.
Blood Cancer Discov
. 2025 Jan;
6(2):110-118.
PMID: 39804695
As survival of HCT recipients continues to improve, late treatment effects gain importance. We demonstrate that pediatric HCT recipients show increased risk of CH compared with age-matched controls. Prospective studies...
5.
Muskens K, Collot-dEscury W, Dandis R, Haitjema S, Kuball J, de Witte M, et al.
Hemasphere
. 2024 Dec;
8(12):e70059.
PMID: 39691452
Despite advances in allogeneic hematopoietic cell transplantation (HCT), poor graft function (PGF) remains an important complication with substantial morbidity and mortality. The investigation of preventive and therapeutic PGF treatments is...
6.
Mohlmann J, Ezzafzafi S, Lindemans C, Jansen M, Nierkens S, Huitema A, et al.
Clin Pharmacokinet
. 2024 Sep;
63(9):1251-1270.
PMID: 39264575
Background And Objective: Systemic corticosteroids have a long history of use in the treatment of autoimmune and inflammatory diseases. Both efficacy and safety show large interindividual variability (IIV), suggesting that...
7.
Koedijk J, van der Werf I, Penter L, Vermeulen M, Barneh F, Perzolli A, et al.
Leukemia
. 2024 Aug;
38(11):2332-2343.
PMID: 39187578
Because of the low mutational burden and consequently, fewer potential neoantigens, children with acute myeloid leukemia (AML) are thought to have a T cell-depleted or 'cold' tumor microenvironment and may...
8.
Beerepoot S, Wolf N, van der Knaap M, Nierkens S, Plantinga M
Mol Immunol
. 2024 Aug;
174:41-46.
PMID: 39182279
Colony stimulating factor 1 receptor (CSF1R) is an essential receptor for both colony stimulating factor 1 (CSF1) and interleukin (IL) 34 signaling expressed on monocyte precursors and myeloid cells, including...
9.
Koenen M, de Steenhuijsen Piters W, de Jonge M, Langereis J, Nierkens S, Chu M, et al.
Eur Respir J
. 2024 Aug;
64(4).
PMID: 39117429
Background: Recurrent respiratory tract infections (rRTIs) are a common reason for immunodiagnostic testing in children, which relies on serum antibody level measurements. However, because RTIs predominantly affect the respiratory mucosa,...
10.
Barneh F, Koedijk J, Wijnen N, Meulendijks T, Ashtiani M, Dunnebach E, et al.
Haematologica
. 2024 Aug;
109(12):4131-4136.
PMID: 39113654
No abstract available.