Stefan M Gaida
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Explore the profile of Stefan M Gaida including associated specialties, affiliations and a list of published articles.
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8
Citations
353
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0
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Recent Articles
1.
Gaida S, Sandoval N, Nicolaou S, Chen Y, Venkataramanan K, Papoutsakis E
Nat Commun
. 2015 May;
6:7045.
PMID: 25944046
A key limitation in using heterologous genomic or metagenomic libraries in functional genomics and genome engineering is the low expression of heterologous genes in screening hosts, such as Escherichia coli....
2.
Gaida S, Al-Hinai M, Indurthi D, Nicolaou S, Papoutsakis E
Nucleic Acids Res
. 2013 Jul;
41(18):8726-37.
PMID: 23892399
Synthetic acid tolerance, especially during active cell growth, is a desirable phenotype for many biotechnological applications. Natively, acid resistance in Escherichia coli is largely a stationary-phase phenotype attributable to mechanisms...
3.
Nicolaou S, Gaida S, Papoutsakis E
Biotechnol J
. 2012 Aug;
7(11):1337-45.
PMID: 22847918
Strain tolerance to toxic chemicals is desirable for biologically producing biofuels and chemicals. Standard genomic libraries can be screened to identify genes imparting tolerance, but cannot capture interactions among proximal...
4.
Nicolaou S, Gaida S, Papoutsakis E
Nucleic Acids Res
. 2011 Oct;
39(22):e152.
PMID: 21976725
In engineering novel microbial strains for biotechnological applications, beyond a priori identifiable pathways to be engineered, it is becoming increasingly important to develop complex, ill-defined cellular phenotypes. One approach is...
5.
Jones S, Tracy B, Gaida S, Papoutsakis E
J Bacteriol
. 2011 Mar;
193(10):2429-40.
PMID: 21421765
Clostridium acetobutylicum is both a model organism for the understanding of sporulation in solventogenic clostridia and its relationship to solvent formation and an industrial organism for anaerobic acetone-butanol-ethanol (ABE) fermentation....
6.
Nicolaou S, Gaida S, Papoutsakis E
Metab Eng
. 2010 Mar;
12(4):307-31.
PMID: 20346409
Metabolites, substrates and substrate impurities may be toxic to cells by damaging biological molecules, organelles, membranes or disrupting biological processes. Chemical stress is routinely encountered in bioprocessing to produce chemicals...
7.
Tracy B, Gaida S, Papoutsakis E
Curr Opin Biotechnol
. 2010 Mar;
21(1):85-99.
PMID: 20206495
Flow cytometry (FC) and FC-based cell sorting have been established as critical tools in modern cell and developmental biology. Yet, their applications in bacteria, especially in the multiparametric mode, remain...
8.
Tracy B, Gaida S, Papoutsakis E
Appl Environ Microbiol
. 2008 Oct;
74(24):7497-506.
PMID: 18931289
The study of microbial heterogeneity at the single-cell level is a rapidly growing area of research in microbiology and biotechnology due to its significance in pathogenesis, environmental biology, and industrial...