Eleftherios T Papoutsakis
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Explore the profile of Eleftherios T Papoutsakis including associated specialties, affiliations and a list of published articles.
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109
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3111
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Recent Articles
1.
Seo H, Capece S, Hill J, Otten J, Papoutsakis E
Metab Eng
. 2024 Oct;
86:194-207.
PMID: 39413987
The butyrate biosynthetic pathway not only contributes to electron management and energy generation in butyrate forming bacteria, but also confers evolutionary advantages to the host by inhibiting the growth of...
2.
Hill J, Papoutsakis E
mSystems
. 2024 Sep;
9(10):e0057224.
PMID: 39254339
Importance: Though dyes and fluorescent reporter proteins have played an essential role in identifying microbial species in co-cultures, we hypothesized that ribosomal RNA-fluorescence hybridization (rRNA-FISH) could be adapted and applied...
3.
Belliveau J, Thompson W, Papoutsakis E
Biotechnol Bioeng
. 2023 Oct;
121(1):118-130.
PMID: 37859509
Chinese hamster ovary (CHO) cells release and exchange large quantities of extracellular vesicles (EVs). EVs are highly enriched in microRNAs (miRs, or miRNAs), which are responsible for most of their...
4.
Jang Y, Kim W, Im J, Palaniswamy S, Yao Z, Lee H, et al.
Metab Eng
. 2023 Apr;
77:188-198.
PMID: 37054966
Here, we report the construction of a Clostridium acetobutylicum strain ATCC 824 (pCD07239) by heterologous expression of carbonyl branch genes (CD630_0723∼CD630_0729) from Clostridium difficile, aimed at installing a heterologous Wood-Ljungdahl...
5.
Funk M, Malo C, Lavine M, Papoutsakis E, Gagne M, Simonti C, et al.
Science
. 2023 Mar;
379(6637):1110-1112.
PMID: 36927024
Highlights from the family of journals.
6.
Belliveau J, Papoutsakis E
Biotechnol Bioeng
. 2023 Feb;
120(9):2700-2716.
PMID: 36788116
A new area of focus in Chinese hamster ovary (CHO) biotechnology is the role of small (exosomes) and large (microvesicles or microparticles) extracellular vesicles (EVs). CHO cells in culture exchange...
7.
Otten J, Zou Y, Papoutsakis E
Front Bioeng Biotechnol
. 2022 Sep;
10:965614.
PMID: 36072287
Caproate (hexanoate) and other medium-chain fatty acids are valuable platform chemicals produced by processes utilizing petroleum or plant oil. , growing on short chain alcohols (notably ethanol) and carboxylic acids...
8.
Kao C, Jiang J, Thompson W, Papoutsakis E
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628168
Megakaryocytes release submicron size microparticles (MkMPs) in circulation. We have shown that MkMPs target CD34+ hematopoietic stem/progenitor cells (HSPCs) to induce megakaryocytic differentiation, and that small RNAs in MkMPs play...
9.
Dahle M, Papoutsakis E, Antoniewicz M
Metab Eng
. 2022 Mar;
72:161-170.
PMID: 35307558
Carbon dioxide-fixing acetogenic bacteria (acetogens) utilizing the Wood-Ljungdahl Pathway (WLP) play an important role in CO fixation in the biosphere and in the development of biological processes - alone or...
10.
Belliveau J, Papoutsakis E
Biotechnol Bioeng
. 2022 Feb;
119(5):1222-1238.
PMID: 35120270
Cells in culture are viewed as unique individuals in a large population communicating through extracellular molecules and, more recently extracellular vesicles (EVs). Our data here paint a different picture: large-scale...