Stefan Kuffer
Overview
Explore the profile of Stefan Kuffer including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
572
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0
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Recent Articles
1.
Hampe L, Kuffer S, Niemeier T, Scheele N, Hampe L, Riedl A, et al.
Front Immunol
. 2025 Jan;
15:1509051.
PMID: 39763660
Background: Esophageal cancer has a poor prognosis despite treatment advancements. Although the benefit of neoadjuvant chemoradiotherapy (CRT) followed by adjuvant immunotherapy is evident, the effects of CRT on PD-L1 expression...
2.
Klein L, Tu M, Krebs N, Urbach L, Grimm D, Latif M, et al.
Nat Commun
. 2025 Jan;
16(1):335.
PMID: 39762215
Pancreatic ductal adenocarcinoma (PDAC) displays a high degree of spatial subtype heterogeneity and co-existence, linked to a diverse microenvironment and worse clinical outcome. However, the underlying mechanisms remain unclear. Here,...
3.
Muller D, Loskutov J, Kuffer S, Marx A, Regenbrecht C, Strobel P, et al.
Cancers (Basel)
. 2024 Aug;
16(15).
PMID: 39123489
Cell culture model systems are fundamental tools for studying cancer biology and identifying therapeutic vulnerabilities in a controlled environment. TET cells are notoriously difficult to culture, with only a few...
4.
Yamada Y, Kuffer S, Sauer C, Hoki M, Shibuya S, Tsujii H, et al.
Virchows Arch
. 2024 Aug;
485(3):461-469.
PMID: 39096416
Metaplastic thymoma (MT), a rare subtype of thymic epithelial tumors (TETs), harbors YAP1::MAML2 fusions. Poroma, a skin tumor, also carries these fusions and exhibits a unique staining pattern for YAP1...
5.
Kuffer S, Muller D, Marx A, Strobel P
Cancers (Basel)
. 2024 Mar;
16(5).
PMID: 38473304
Thymomas (THs) are a unique group of heterogeneous tumors of the thymic epithelium. In particular, the subtypes B2 and B3 tend to be aggressive and metastatic. Radical tumor resection remains...
6.
Netzer C, von Arps-Aubert V, Macinkovic I, von der Grun J, Kuffer S, Strobel P, et al.
Front Immunol
. 2024 Feb;
14:1240394.
PMID: 38322012
Background: Interactions between tumor cells and cells in the microenvironment contribute to tumor development and metastasis. The spatial arrangement of individual cells in relation to each other influences the likelihood...
7.
Bremmer F, Pongratanakul P, Skowron M, Che Y, Richter A, Kuffer S, et al.
Br J Cancer
. 2023 Sep;
129(10):1580-1589.
PMID: 37726478
Background: Germ cell tumors (GCT) might undergo transformation into a somatic-type malignancy (STM), resulting in a cell fate switch to tumors usually found in somatic tissues, such as rhabdomyosarcomas or...
8.
Pfisterer N, Ammer-Herrmenau C, Antweiler K, Kuffer S, Ellenrieder V, Neesse A
Pancreatology
. 2023 Aug;
23(6):663-673.
PMID: 37541802
Background: Emerging evidence has recently revealed a prominent role of the microbiome in pancreatic ductal adenocarcinoma (PDAC). However, while most observations were made in patients, mouse models still require a...
9.
Bremmer F, Bohnenberger H, Findeisen P, Welter S, Von Hammerstein-Equord A, Hinterthaner M, et al.
Histopathology
. 2023 Jun;
83(4):607-616.
PMID: 37308176
Aims: The reliable classification of type A versus type B3 thymomas has prognostic and therapeutic relevance, but can be problematic due to considerably overlapping morphology. No immunohistochemical markers aiding in...
10.
Skowron M, Kotthoff M, Bremmer F, Ruhnke K, Parmaksiz F, Richter A, et al.
Mol Med
. 2023 Mar;
29(1):40.
PMID: 36991316
Background: Being the standard-of-care for four decades, cisplatin-based chemotherapy is highly efficient in treating germ cell tumors (GCT). However, often refractory patients present with a remaining (resistant) yolk-sac tumor (YST(-R))...