Philipp Strobel
Overview
Explore the profile of Philipp Strobel including associated specialties, affiliations and a list of published articles.
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Articles
326
Citations
6351
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Recent Articles
1.
Functional apoptosis profiling reveals vulnerabilities in T-cell large granular lymphocytic leukemia
Shumilov E, Mazzeo P, Trautmann M, Levien L, Menck K, Richter K, et al.
Ann Hematol
. 2025 Feb;
104(1):581-591.
PMID: 39912943
T-cell large granular lymphocytic leukemia (T-LGLL) is a rare hematologic neoplasm characterized by clonal expansion of CD3 + cytotoxic T lymphocytes and a highly heterogeneous clinical course. Conventional therapy primarily...
2.
Jebran A, Seidler T, Tiburcy M, Daskalaki M, Kutschka I, Fujita B, et al.
Nature
. 2025 Jan;
639(8054):503-511.
PMID: 39880949
Cardiomyocytes can be implanted to remuscularize the failing heart. Challenges include sufficient cardiomyocyte retention for a sustainable therapeutic impact without intolerable side effects, such as arrhythmia and tumour growth. We...
3.
Marx A, Strobel P
Pathologie (Heidelb)
. 2025 Jan;
46(1):62-73.
PMID: 39873801
After describing the anatomy of the spleen and the most important immunohistochemical stains for identifying cellular constituents of the normal splenic compartments, etiologies of splenomegaly and the diagnostic approach for...
4.
Bleyer M, Radespiel U, Klein A, Kollikowski A, Strobel P, Matz-Rensing K, et al.
J Comp Pathol
. 2024 Nov;
215:47-54.
PMID: 39520914
Mouse lemurs (Microcebus spp) are small Madagascan strepsirrhine primates increasingly used as an animal model in ageing research. During a period of 10 years, neoplastic disease occurred in 47 grey...
5.
Tirilomi A, Tirilomis P, Elakad O, Yao S, Hinterthaner M, Danner B, et al.
Medicine (Baltimore)
. 2024 Oct;
103(40):e39911.
PMID: 39465762
Malignant tumors of the lung are the leading cancers worldwide. Prognostic biomarkers continue to be investigated for the detection and stratification of lung cancer for clinical use. In breast cancer...
6.
Menzel M, Martis-Thiele M, Goldschmid H, Ott A, Romanovsky E, Siemanowski-Hrach J, et al.
Eur J Cancer
. 2024 Sep;
211:114306.
PMID: 39293347
Introduction: Whole Exome Sequencing (WES) has emerged as an efficient tool in clinical cancer diagnostics to broaden the scope from panel-based diagnostics to screening of all genes and enabling robust...
7.
Tapia Contreras C, Falke J, Seifert D, Schneider C, Krauss L, Fang X, et al.
Mol Oncol
. 2024 Sep;
19(2):295-310.
PMID: 39253995
Pancreatic ductal adenocarcinoma (PDAC) has limited treatment options, emphasizing the urgent need for effective therapies. The predominant driver in PDAC is mutated KRAS proto-oncogene, KRA, present in 90% of patients....
8.
Aich A, Boshnakovska A, Witte S, Gall T, Unthan-Fechner K, Yousefi R, et al.
Nat Commun
. 2024 Aug;
15(1):6914.
PMID: 39134548
Mitochondrial oxidative phosphorylation (OXPHOS) fuels cellular ATP demands. OXPHOS defects lead to severe human disorders with unexplained tissue specific pathologies. Mitochondrial gene expression is essential for OXPHOS biogenesis since core...
9.
Muller D, Loskutov J, Kuffer S, Marx A, Regenbrecht C, Strobel P, et al.
Cancers (Basel)
. 2024 Aug;
16(15).
PMID: 39123489
Cell culture model systems are fundamental tools for studying cancer biology and identifying therapeutic vulnerabilities in a controlled environment. TET cells are notoriously difficult to culture, with only a few...
10.
Schneider C, Hilbert J, Genevaux F, Hofer S, Krauss L, Schicktanz F, et al.
Adv Sci (Weinh)
. 2024 Jun;
11(31):e2307695.
PMID: 38885414
Cancer cells must develop strategies to adapt to the dynamically changing stresses caused by intrinsic or extrinsic processes, or therapeutic agents. Metabolic adaptability is crucial to mitigate such challenges. Considering...