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Stefan Gloggler

Explore the profile of Stefan Gloggler including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 626
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Recent Articles
1.
Fries L, Montrazi E, Allouche-Arnon H, Opazo F, Bar-Shir A, Frydman L, et al.
Nano Lett . 2025 Jan; 25(5):1758-1764. PMID: 39841010
Deuterium (H) MRI is an emerging tool for noninvasive imaging. We explore the integration of H MRI with deuterated multifunctional nanopolymers for deuterated particle imaging (DPI). To this end, amine-terminated...
2.
Santi M, Hune T, Rodriguez G, Fries L, Mei R, Sternkopf S, et al.
Analyst . 2024 Sep; 149(20):5022-5033. PMID: 39230365
Alterations in pH are a hallmark in several pathologies including cancer, ischemia, and inflammation. Non-invasive magnetic resonance methods to measure pH offer a new approach for early diagnosis of diseases...
3.
Fries L, Hune T, Sternkopf S, Mamone S, Schneider K, Schulz-Heddergott R, et al.
Chemistry . 2024 Jun; 30(51):e202400187. PMID: 38887134
Parahydrogen-induced polarization (PHIP) is an emerging technique to enhance the signal of stable isotope metabolic contrast agents for Magnetic Resonance (MR). The objective of this study is to continue establishing...
4.
Mei R, Fries L, Hune T, Santi M, Rodriguez G, Sternkopf S, et al.
Angew Chem Int Ed Engl . 2024 May; 63(33):e202403144. PMID: 38773847
Magnetic resonance with hyperpolarized contrast agents is one of the most powerful and noninvasive imaging platforms capable for investigating in vivo metabolism. While most of the utilized hyperpolarized agents are...
5.
Jagtap A, Mamone S, Gloggler S
Magn Reson Chem . 2023 Oct; 61(12):674-680. PMID: 37821237
Enhancing magnetic resonance signal via hyperpolarization techniques enables the real-time detection of metabolic transformations even in vivo. The use of para-hydrogen to enhance C-enriched metabolites has opened a rapid pathway...
6.
Ding Y, Stevanato G, von Bonin F, Kube D, Gloggler S
Chem Sci . 2023 Jul; 14(28):7642-7647. PMID: 37476713
Signal-enhanced or hyperpolarized nuclear magnetic resonance (NMR) spectroscopy stands out as a unique tool to monitor real-time enzymatic reactions in living cells. The singlet state of para-hydrogen is thereby one...
7.
de Maissin H, Gross P, Mohiuddin O, Weigt M, Nagel L, Herzog M, et al.
Angew Chem Int Ed Engl . 2023 Jul; 62(36):e202306654. PMID: 37439488
Metabolic magnetic resonance imaging (MRI) using hyperpolarized (HP) pyruvate is becoming a non-invasive technique for diagnosing, staging, and monitoring response to treatment in cancer and other diseases. The clinically established...
8.
Stevanato G, Ding Y, Mamone S, Jagtap A, Korchak S, Gloggler S
J Am Chem Soc . 2023 Mar; 145(10):5864-5871. PMID: 36857108
In recent years, parahydrogen-induced polarization side arm hydrogenation (PHIP-SAH) has been applied to hyperpolarize [1-C]pyruvate and map its metabolic conversion to [1-C]lactate in cancer cells. Developing on our recent MINERVA...
9.
Lysak D, Kock F, Mamone S, Soong R, Gloggler S, Simpson A
Chem Sci . 2023 Feb; 14(6):1413-1418. PMID: 36794179
In line with recent paradigm shifts in toxicity testing, nuclear magnetic resonance (NMR) is a powerful tool for studying the biological impacts and perturbations caused by toxicants in living organisms....
10.
Hune T, Mamone S, Schroeder H, Jagtap A, Sternkopf S, Stevanato G, et al.
Chemphyschem . 2022 Sep; 24(2):e202200615. PMID: 36106366
The metabolism of malignant cells differs significantly from that of healthy cells and thus, it is possible to perform metabolic imaging to reveal not only the exact location of a...