Stanley J Watowich
Overview
Explore the profile of Stanley J Watowich including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
790
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0
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Recent Articles
21.
Tomlinson S, Watowich S
Antiviral Res
. 2010 Dec;
89(2):127-35.
PMID: 21185332
Dengue virus (DENV) is a mosquito-borne flavivirus that has strained global healthcare systems throughout tropical and subtropical regions of the world. In addition to plaguing developing nations, it has re-emerged...
22.
Russo A, Malmstrom R, White M, Watowich S
J Mol Graph Model
. 2010 May;
29(1):46-53.
PMID: 20483643
The alphavirus nsP2 protease is essential for correct processing of the alphavirus nonstructural polyprotein (nsP1234) and replication of the viral genome. We have combined molecular dynamics simulations with our structural...
23.
Luke T, Casadevall A, Watowich S, Hoffman S, Beigel J, Burgess T
Crit Care Med
. 2010 Feb;
38(4 Suppl):e66-73.
PMID: 20154602
The world is experiencing a pandemic of swine-origin influenza virus H1N1. A vaccine to prevent disease is now available, and millions have or will become ill before they can be...
24.
Tomlinson S, Malmstrom R, Russo A, Mueller N, Pang Y, Watowich S
Antiviral Res
. 2009 May;
82(3):110-4.
PMID: 19428601
Dengue virus belongs to the family Flaviviridae and is a major emerging pathogen for which the development of vaccines and antiviral therapy has seen little success. The NS3 viral protease...
25.
Campbell R, Yang Y, Wang T, Rachamallu A, Li Y, Watowich S, et al.
Methods Enzymol
. 2009 Apr;
456:363-80.
PMID: 19348899
Viral infections frequently alter mitochondrial function with suppression or induction of apoptosis and enhanced generation of reactive oxygen species. The mechanisms of these effects are varied, and mitochondria are affected...
26.
Sherman M, Freiberg A, Holbrook M, Watowich S
Virology
. 2009 Mar;
387(1):11-5.
PMID: 19304307
Rift Valley fever virus (RVFV; Bunyaviridae; Phlebovirus) is an emerging human and veterinary pathogen causing acute hepatitis in ruminants and has the potential to cause hemorrhagic fever in humans. We...
27.
Tomlinson S, Watowich S
Biochemistry
. 2008 Oct;
47(45):11763-70.
PMID: 18855422
West Nile virus (WNV) has recently emerged in North America as a significant disease threat to humans and animals. Unfortunately, no approved antiviral drugs exist to combat WNV or other...
28.
Freiberg A, Sherman M, Morais M, Holbrook M, Watowich S
J Virol
. 2008 Aug;
82(21):10341-8.
PMID: 18715915
Rift Valley fever virus (RVFV) is a member of the Bunyaviridae virus family (genus Phlebovirus) and is considered to be one of the most important pathogens in Africa, causing viral...
29.
Kolokoltsova O, Domina A, Kolokoltsov A, Davey R, Weaver S, Watowich S
Virology
. 2008 May;
377(1):133-42.
PMID: 18485440
Virus-host interactions essential for alphavirus pathogenesis are poorly understood. To address this shortcoming, we coupled retrovirus insertional mutagenesis and a cell survival selection strategy to generate clonal cell lines broadly...
30.
Sheth P, Hays J, Elferink L, Watowich S
Biochemistry
. 2008 Mar;
47(13):4028-38.
PMID: 18324780
Ligand-induced dimerization of receptor tyrosine kinases (RTKs) modulates a system of linked biochemical reactions, sharply switching the RTK from a quiescent state to an active state that becomes phosphorylated and...