Stanley Ching-Cheng Huang
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Explore the profile of Stanley Ching-Cheng Huang including associated specialties, affiliations and a list of published articles.
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7480
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Recent Articles
1.
Jin J, Zhang R, Li J, Gao F, Liao Z, Yu Y, et al.
Proc Natl Acad Sci U S A
. 2025 Mar;
122(10):e2424061122.
PMID: 40030035
Optimal activation of CD8+ T cells is crucial for immunity-mediated destruction of cancer, requiring a substantial amount of proteins involved in metabolism, proliferation, and effector function. Despite extensive studies emphasizing...
2.
Andrews J, Zhang Z, Prasad G, Huey F, Nazarova E, Wang J, et al.
Mucosal Immunol
. 2024 Jun;
17(5):825-842.
PMID: 38844208
Mycobacterium tuberculosis (Mtb)-infected neutrophils are often found in the airways of patients with active tuberculosis (TB), and excessive recruitment of neutrophils to the lung is linked to increased bacterial burden...
3.
Li Y, Wu S, Zhao Y, Dinh T, Jiang D, Selfridge J, et al.
J Clin Invest
. 2024 Jan;
134(5).
PMID: 38194275
Neutrophil extracellular traps (NETs), a web-like structure of cytosolic and granule proteins assembled on decondensed chromatin, kill pathogens and cause tissue damage in diseases. Whether NETs can kill cancer cells...
4.
Zhang K, Zakeri A, Alban T, Dong J, Ta H, Zalavadia A, et al.
Cell Rep
. 2024 Jan;
43(1):113661.
PMID: 38175754
Myeloid-derived suppressor cells (MDSCs) impair antitumor immune responses. Identifying regulatory circuits during MDSC development may bring new opportunities for therapeutic interventions. We report that the V-domain suppressor of T cell...
5.
Dang B, Gao Q, Zhang L, Zhang J, Cai H, Zhu Y, et al.
Cell Rep
. 2023 May;
42(5):112471.
PMID: 37149865
T helper type 2 (Th2) cytokine-activated M2 macrophages contribute to inflammation resolution and wound healing. This study shows that IL-4-primed macrophages exhibit a stronger response to lipopolysaccharide stimulation while maintaining...
6.
Raines L, Huang S
Immunohorizons
. 2023 Apr;
7(4):256-264.
PMID: 37067519
The correct folding of proteins is essential for appropriate cell function and is tightly regulated within the endoplasmic reticulum (ER). Environmental challenges and cellular conditions disrupt ER homeostasis and induce...
7.
Di Conza G, Ho P, Cubillos-Ruiz J, Huang S
Nat Rev Immunol
. 2023 Feb;
23(9):546-562.
PMID: 36755160
Initiating and maintaining optimal immune responses requires high levels of protein synthesis, folding, modification and trafficking in leukocytes, which are processes orchestrated by the endoplasmic reticulum. Importantly, diverse extracellular and...
8.
Andrews J, Voth D, Huang S, Huang L
Front Cell Infect Microbiol
. 2022 Jul;
12:934460.
PMID: 35899042
Lung macrophages are substantially distinct from other tissue-resident macrophages. They act as frontier sentinels of the alveolar-blood interface and are constantly exposed to various pathogens. Additionally, they precisely regulate immune...
9.
Wang W, Kasamatsu J, Joshita S, Gilfillan S, Luccia B, Panda S, et al.
Proc Natl Acad Sci U S A
. 2022 Jun;
119(23):e2204557119.
PMID: 35653568
C-type lectin domain family 4, member a4 (Clec4a4) is a C-type lectin inhibitory receptor specific for glycans thought to be exclusively expressed on murine CD8α− conventional dendritic cells. Using newly...
10.
Raines L, Zhao H, Wang Y, Chen H, Gallart-Ayala H, Hsueh P, et al.
Nat Immunol
. 2022 Mar;
23(3):431-445.
PMID: 35228694
Chronic inflammation triggers compensatory immunosuppression to stop inflammation and minimize tissue damage. Studies have demonstrated that endoplasmic reticulum (ER) stress augments the suppressive phenotypes of immune cells; however, the molecular...