Stanislav Y Shvartsman
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Explore the profile of Stanislav Y Shvartsman including associated specialties, affiliations and a list of published articles.
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166
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3217
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Recent Articles
1.
Avdeeva M, Chalifoux M, Joyce B, Shvartsman S, Posfai E
bioRxiv
. 2025 Mar;
PMID: 40060535
The first cell fate bifurcation in mammalian development directs cells toward either the trophectoderm (TE) or inner cell mass (ICM) compartments in preimplantation embryos. This decision is regulated by the...
2.
Kilwein M, Miller P, Lee K, Osterfield M, Mogilner A, Shvartsman S, et al.
Curr Biol
. 2025 Mar;
PMID: 40049172
Germline-soma segregation is crucial for fertility. Primordial germ cells (PGCs) arise early in development and are the very first cells to form in the Drosophila embryo. At the time of...
3.
Ho E, Kim-Yip R, Simpkins A, Farahani P, Oatman H, Posfai E, et al.
bioRxiv
. 2025 Jan;
PMID: 39829924
A lack of tools for detecting receptor activity has limited our ability to fully explore receptor-level control of developmental patterning. Here, we extend a new class of biosensors for receptor...
4.
Levy E, Leite I, Joyce B, Shvartsman S, Posfai E
Curr Biol
. 2024 Nov;
34(24):5728-5738.e4.
PMID: 39566500
Gametes in many species develop in cysts-clusters of germ cells formed by incomplete cytokinesis-that remain connected through intercellular bridges (ICBs). These connections enable sharing of cytoplasmic components between germ cells...
5.
Denberg D, Zhang X, Stern T, Wieschaus E, Garikipati K, Shvartsman S
Biophys J
. 2024 Oct;
123(22):3911-3922.
PMID: 39385470
Gastrulation is a critical process during embryonic development that transforms a single-layered blastula into a multilayered embryo with distinct germ layers, which eventually give rise to all the tissues and...
6.
Nunley H, Shao B, Denberg D, Grover P, Singh J, Avdeeva M, et al.
Development
. 2024 Oct;
151(21).
PMID: 39373366
For investigations into fate specification and morphogenesis in time-lapse images of preimplantation embryos, automated 3D instance segmentation and tracking of nuclei are invaluable. Low signal-to-noise ratio, high voxel anisotropy, high...
7.
Smart M, Shvartsman S, Monnigmann M
Proc Natl Acad Sci U S A
. 2024 Oct;
121(41):e2409330121.
PMID: 39365818
Habituation-a phenomenon in which a dynamical system exhibits a diminishing response to repeated stimulations that eventually recovers when the stimulus is withheld-is universally observed in living systems from animals to...
8.
Gavrilchenko T, Simpkins A, Simpson T, Barrett L, Hansen P, Shvartsman S, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(41):e2404462121.
PMID: 39356666
The terminal cells of the larval tracheal system are perhaps the simplest delivery networks, providing an analogue for mammalian vascular growth and function in a system with many fewer components....
9.
Yang L, Zhu A, Aman J, Denberg D, Kilwein M, Marmion R, et al.
Dev Cell
. 2024 Aug;
59(23):3061-3071.e6.
PMID: 39208802
Extracellular-signal-regulated kinase (ERK) signaling controls development and homeostasis and is genetically deregulated in human diseases, including neurocognitive disorders and cancers. Although the list of ERK functions is vast and steadily...
10.
Chakrabarti B, Rachh M, Shvartsman S, Shelley M
Proc Natl Acad Sci U S A
. 2024 Jul;
121(30):e2405114121.
PMID: 39012825
Large cells often rely on cytoplasmic flows for intracellular transport, maintaining homeostasis, and positioning cellular components. Understanding the mechanisms of these flows is essential for gaining insights into cell function,...