Ssang-Taek Steve Lim
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Explore the profile of Ssang-Taek Steve Lim including associated specialties, affiliations and a list of published articles.
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22
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Recent Articles
1.
Murphy J, Tran D, Jeong K, Nguyen L, Nguyen M, Tambe D, et al.
bioRxiv
. 2024 Dec;
PMID: 39677751
Atherosclerosis develops at predictable sites in the vasculature where branch points and curvatures create non-laminar disturbed flow. This disturbed flow causes vascular inflammation by increased endothelial cell (EC) barrier permeability...
2.
Murphy J, Jeong K, Ahn E, Lim S
bioRxiv
. 2024 Dec;
PMID: 39651254
Epigenetic silencing of tumor suppressor genes is one of the main drivers of tumor progression. Without these tumor suppressors to reduce proliferation, tumor cells proliferate unchecked. Focal adhesion kinase (FAK)...
3.
Phillips J, Park S, Lin C, Cho J, Lim S, Aurora R, et al.
Br J Cancer
. 2024 Sep;
131(9):1437-1449.
PMID: 39313574
Background: In breast cancer, ErbB receptors play a critical role, and overcoming drug resistance remains a major challenge in the clinic. However, intricate regulatory mechanisms of ErbB family genes are...
4.
Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, et al.
JCI Insight
. 2024 Jan;
9(5).
PMID: 38290089
Rare diseases are underrepresented in biomedical research, leading to insufficient awareness. Zhu-Tokita-Takenouchi-Kim (ZTTK) syndrome is a rare disease caused by genetic alterations that result in heterozygous loss of function of...
5.
Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, et al.
bioRxiv
. 2023 Nov;
PMID: 38014320
Rare diseases are underrepresented in biomedical research, leading to insufficient awareness. Zhu-Tokita-Takenouchi-Kim (ZTTK) syndrome is a rare disease caused by genetic alterations that result in heterozygous loss-of-function of SON. While...
6.
Murphy J, Jeong K, Tran D, Cioffi D, Campbell P, Kim J, et al.
Atherosclerosis
. 2023 Aug;
379:117189.
PMID: 37527611
Background And Aims: Hyperlipidemia leads to the accumulation of oxidized low-density lipoprotein (oxLDL) within the vessel wall where it causes chronic inflammation in endothelial cells (ECs) and drives atherosclerotic lesions....
7.
Kim J, Lim S
Curr Issues Mol Biol
. 2022 Jun;
44(3):1235-1246.
PMID: 35723305
In this study, changes in cell signaling mechanisms in skin cells induced by various wavelengths and intensities of light-emitting diodes (LED) were investigated, focusing on the activity of focal adhesion...
8.
Murphy J, Jeong K, Ahn E, Lim S
J Biol Chem
. 2022 May;
298(6):102013.
PMID: 35525274
Dysregulation of cyclin-dependent kinases (CDKs) can promote unchecked cell proliferation and cancer progression. Although focal adhesion kinase (FAK) contributes to regulating cell cycle progression, the exact molecular mechanism remains unclear....
9.
Jeong K, Murphy J, Kim J, Campbell P, Park H, Rodriguez Y, et al.
Circ Res
. 2021 Oct;
129(12):e215-e233.
PMID: 34702049
Rationale: Vascular smooth muscle cells (SMCs) exhibit remarkable plasticity and can undergo dedifferentiation upon pathological stimuli associated with disease and interventions. Objective: Although epigenetic changes are critical in SMC phenotype...
10.
Jeong K, Murphy J, Ahn E, Lim S
Cardiovasc Res
. 2021 Apr;
118(4):1150-1163.
PMID: 33839758
Aims: Vascular smooth muscle cells (VSMCs) normally exhibit a very low proliferative rate. Vessel injury triggers VSMC proliferation, in part, through focal adhesion kinase (FAK) activation, which increases transcription of...