Srinivasa M Srinivasula
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Explore the profile of Srinivasa M Srinivasula including associated specialties, affiliations and a list of published articles.
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34
Citations
4287
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Recent Articles
1.
Sharma R, Dey Das K, Srinivasula S
Cell Rep
. 2024 Oct;
43(11):114896.
PMID: 39441718
In mammalian cells, the Golgi exists in ribbon architecture-individual stacks laterally linked to each other by tubular structures. Golgi architecture changes dynamically to cater to cellular needs. Loss of architecture...
2.
Sharma R, Mondal P, Srinivasula S
FEBS J
. 2023 Feb;
290(14):3580-3594.
PMID: 36853170
The development of neurological pathologies is linked to the accumulation of protein aggregates like alpha-synuclein in Parkinson's disease and tau protein in Alzheimer's disease. Mono- or di-ubiquitination of these molecules...
3.
Ravindran R, Velikkakath A, Dev Narendradev N, Chandrasekharan A, Santhoshkumar T, Srinivasula S
Autophagy
. 2022 Apr;
18(12):2851-2864.
PMID: 35373701
Mutations in the ubiquitin ligase PRKN (parkin RBR E3 ubiquitin protein ligase) are associated with Parkinson disease and defective mitophagy. Conceptually, PRKN-dependent mitophagy is classified into two phases: 1. PRKN...
4.
Reselammal D, Pinhero F, Sharma R, Oliyantakath Hassan M, Srinivasula S, Vijayan V
J Mol Biol
. 2021 Jun;
433(15):167084.
PMID: 34081983
Long-term memory storage is modulated by the prion nature of CPEB3 forming the molecular basis for the maintenance of synaptic facilitation. Here we report that the first prion sub-domain PRD1...
5.
Suma P, Padmanabhan R, Telukutla S, Ravindran R, Velikkakath A, Dekiwadia C, et al.
Free Radic Biol Med
. 2020 Oct;
161:198-211.
PMID: 33065180
The redox-active transition metals such as copper, iron, chromium, vanadium, and silica are known for its ROS generation via mechanisms such as Haber-Weiss and Fenton-type reactions. Nanoparticles of these metals...
6.
Nair S, Dev Narendradev N, Nambiar R, Kumar R, Srinivasula S
J Cell Sci
. 2020 May;
133(11).
PMID: 32409562
Lysosomal exocytosis and resealing of damaged plasma membrane are essential for cellular homeostasis and tumor invasion. However, very little is known of the molecular machinery that regulates these physiological processes....
7.
Klionsky D, Abdalla F, Abeliovich H, Abraham R, Acevedo-Arozena A, Adeli K, et al.
Autophagy
. 2012 Sep;
8(4):445-544.
PMID: 22966490
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered...
8.
Srinivasula S, Ashwell J
Mol Cell
. 2011 Nov;
44(4):511-2.
PMID: 22099299
In this issue of Molecular Cell, Skaug et al. (2011) propose a polyubiquitin-dependent, noncatalytic mechanism by which the deubiquitinase A20 inhibits IκB kinase and NF-κB activation.
9.
Fujita K, Srinivasula S
Autophagy
. 2011 Mar;
7(5):552-4.
PMID: 21412052
Autophagy plays an evolutionarily conserved role in host defense against pathogens. Autophagic protection mechanisms against microbes range from regulating immune signaling responses to directly targeting the pathogens for lysosomal degradation....
10.
Fujita K, Maeda D, Xiao Q, Srinivasula S
Proc Natl Acad Sci U S A
. 2011 Jan;
108(4):1427-32.
PMID: 21220332
Toll-like receptors (TLRs) play a crucial role in several innate immune responses by regulating autophagy, but little is known about how TLR signaling controls autophagy. Here we demonstrate that p62/SQSTM1...