Sridharan Rajamani
Overview
Explore the profile of Sridharan Rajamani including associated specialties, affiliations and a list of published articles.
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74
Citations
1631
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Recent Articles
1.
Wisialowski T, Ether N, Foley C, Kleiman R, Koshman Y, Leishman D, et al.
J Pharmacol Toxicol Methods
. 2024 May;
128:107515.
PMID: 38777240
No abstract available.
2.
Darkow E, Yusuf D, Rajamani S, Backofen R, Kohl P, Ravens U, et al.
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37446137
The cardiac cell mechanical environment changes on a beat-by-beat basis as well as in the course of various cardiac diseases. Cells sense and respond to mechanical cues via specialized mechano-sensors...
3.
Thorolfsdottir R, Sveinbjornsson G, Aegisdottir H, Benonisdottir S, Stefansdottir L, Ivarsdottir E, et al.
Eur Heart J
. 2022 Oct;
42(20):1959-1971.
PMID: 36282123
Aims: The aim of this study was to use human genetics to investigate the pathogenesis of sick sinus syndrome (SSS) and the role of risk factors in its development. Methods...
4.
Ge H, Liu G, Yamawaki T, Tao C, Alexander S, Ly K, et al.
Sci Rep
. 2021 Sep;
11(1):17449.
PMID: 34465831
Heart failure (HF) and cardiac arrhythmias share overlapping pathological mechanisms that act cooperatively to accelerate disease pathogenesis. Cardiac fibrosis is associated with both pathological conditions. Our previous work identified a...
5.
Darkow E, Nguyen T, Stolina M, Kari F, Schmidt C, Wiedmann F, et al.
Front Physiol
. 2021 Apr;
12:650964.
PMID: 33868017
In search of more efficacious and safe pharmacological treatments for atrial fibrillation (AF), atria-selective antiarrhythmic agents have been promoted that target ion channels principally expressed in the atria. This concept...
6.
Thorolfsdottir R, Sveinbjornsson G, Aegisdottir H, Benonisdottir S, Stefansdottir L, Ivarsdottir E, et al.
Eur Heart J
. 2021 Feb;
42(20):1959-1971.
PMID: 33580673
Aims: The aim of this study was to use human genetics to investigate the pathogenesis of sick sinus syndrome (SSS) and the role of risk factors in its development. Methods...
7.
Rivaud M, Marchal G, Wolswinkel R, Jansen J, van der Made I, Beekman L, et al.
Europace
. 2020 Aug;
22(10):1579-1589.
PMID: 32778883
Aims: SCN5A mutations are associated with arrhythmia syndromes, including Brugada syndrome, long QT syndrome type 3 (LQT3), and cardiac conduction disease. Long QT syndrome type 3 patients display atrio-ventricular (AV)...
8.
Ang Y, Rajamani S, Haldar S, Huser J
Circ Res
. 2020 Jul;
127(1):184-201.
PMID: 32717173
Atrial fibrillation (AF) is a highly prevalent cardiac arrhythmia and cause of significant morbidity and mortality. Its increasing prevalence in aging societies constitutes a growing challenge to global healthcare systems....
9.
Hwang J, Kim T, Terentyev D, Zhong M, Kabakov A, Bronk P, et al.
Circ Arrhythm Electrophysiol
. 2020 Jul;
13(8):e006875.
PMID: 32628505
Background: Long QT syndrome has been associated with sudden cardiac death likely caused by early afterdepolarizations (EADs) and polymorphic ventricular tachycardias (PVTs). Suppressing the late sodium current (I) may counterbalance...
10.
Ason B, Chen Y, Guo Q, Hoagland K, Chui R, Fielden M, et al.
JCI Insight
. 2020 Mar;
5(8).
PMID: 32208384
Heart failure (HF) remains a grievous illness with poor prognosis even with optimal care. The apelin receptor (APJ) counteracts the pressor effect of angiotensin II, attenuates ischemic injury, and has...