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Souren Paul

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Articles 24
Citations 279
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Recent Articles
11.
Chauhan A, Bahuguna A, Paul S, Kang S
Anticancer Agents Med Chem . 2017 Mar; 17(14):1942-1950. PMID: 28356011
Background: Colon cancer is one of the most deadly and common carcinomas occurring worldwide and there have been many attempts to treat this cancer. The present work was designed in...
12.
Khan I, Paul S, Jakhar R, Bhardwaj M, Han J, Kang S
Biomed Pharmacother . 2016 Oct; 84:789-799. PMID: 27721177
Although quercetin is very well known for its anticancer activity, however it shows some drawbacks. Herein, we have evaluated the apoptotic effect TEF (5, 3'-dihydroxy-3, 7, 4'-triethoxyflavone), a newly synthesized...
13.
Bhardwaj M, Kim N, Paul S, Jakhar R, Han J, Kang S
PLoS One . 2016 Apr; 11(4):e0154525. PMID: 27116119
Plant-derived compounds are an important source of clinically useful anti-cancer agents. Chrysin, a biologically active flavone found in many plants, has limited usage for cancer chemotherapeutics due to its poor...
14.
Jakhar R, Paul S, Bhardwaj M, Kang S
Cancer Lett . 2016 Jan; 372(1):89-100. PMID: 26739061
Apoptosis and autophagy are genetically regulated, evolutionarily conserved processes that can jointly seal cancer cell fates, and numerous death stimuli are capable of activating either pathway. Although crosstalk between apoptosis...
15.
Kim D, Roh E, Lee M, Oi N, Lim D, Kim M, et al.
Cancer Res . 2015 Dec; 76(5):1146-1157. PMID: 26676750
Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis that is associated with cell growth and tumor formation. Existing catalytic inhibitors of ODC have lacked...
16.
Jung H, Kim H, Paul S, Jang J, Cho Y, Kim H, et al.
Saudi J Biol Sci . 2015 Nov; 22(6):706-13. PMID: 26586997
In this study, the effect of purified quercetin-3-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranosid (QCGG) on melanogenesis was investigated. QCGG was isolated from the calyx of a traditional Korean medicinal herb, Persimmon (Diospyros kaki)....
17.
Paul S, Jakhar R, Bhardwaj M, Kang S
Free Radic Biol Med . 2015 Nov; 89:1218-30. PMID: 26561775
Aflatoxin B1 (AFB1) is the most toxic aflatoxin species and has been shown to be associated with specific as well as non-specific immune responses. In the present study, using murine...
18.
Bhardwaj M, Paul S, Jakhar R, Kang S
Life Sci . 2015 Oct; 142:36-48. PMID: 26475763
Aims: Cells possess multiple methods for counteracting the deleterious consequences of stress induced by physical and chemical stimuli. Heat stress causes variations in the cellular environment, leading to cellular morbidity...
19.
Jakhar R, Paul S, Chauhan A, Kang S
Int Immunopharmacol . 2014 Jul; 22(2):356-65. PMID: 25068824
Morin, a natural flavonoid that is the primary bioactive constituent of the family Moraceae, has been found to be associated with many therapeutic properties. In this study, we evaluated the...
20.
Jakhar R, Paul S, Park Y, Han J, Kang S
J Photochem Photobiol B . 2014 Feb; 131:96-103. PMID: 24514458
DNA protection is one of the most important strategies in cancer therapy. Since quercetin and its derivatives are found to be potent antioxidant agents, they are able to scavenge radicals...