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Souren Paul

Explore the profile of Souren Paul including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 279
Followers 0
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Recent Articles
1.
McCourt P, Day C, Paul S
Front Pharmacol . 2025 Feb; 16:1519429. PMID: 39944621
No abstract available.
2.
Day C, Grigore F, Hakkim F, Paul S, Langfald A, Weberg M, et al.
Curr Biol . 2024 Dec; 35(2):354-362.e7. PMID: 39729988
Serine 31 is a phospho-site unique to the histone H3.3 variant; mitotic phospho-Ser31 is restricted to pericentromeric heterochromatin, and disruption of phospho-Ser31 results in chromosome segregation defects and loss of...
3.
Paul S, McCourt P, Le L, Ryu J, Czaja W, Bode A, et al.
bioRxiv . 2023 Oct; PMID: 37873235
Telomeres protect chromosome ends and determine the replication potential of dividing cells. The canonical telomere sequence TTAGGG is synthesized by telomerase holoenzyme, which maintains telomere length in proliferative stem cells....
4.
Paul S, Kaplan M, Khanna D, McCourt P, Saha A, Tsou P, et al.
Nat Commun . 2022 Nov; 13(1):7074. PMID: 36400785
Centromere defects in Systemic Sclerosis (SSc) have remained unexplored despite the fact that many centromere proteins were discovered in patients with SSc. Here we report that lesion skin fibroblasts from...
5.
Paul S, Bhardwaj M, Kang S
Int J Oncol . 2022 Sep; 61(5). PMID: 36129143
The aim of the present study was to decipher the mechanism of glutathione‑S‑transferase Ω‑1 (GSTO1)‑induced drug resistance in colon cancer cells. Cisplatin is used widely as a therapeutic drug in...
6.
Paul S, Jakhar R, Bhardwaj M, Chauhan A, Kang S
Food Chem Toxicol . 2021 Jun; 154:112326. PMID: 34111490
Fumonisin B1 (FB1) is a well-known mycotoxin produced by Fusarium spp. and has a wide range of dose-dependent toxic effects, including nephrotoxicity, hepatotoxicity, and neurotoxicity. This research illustrated that FB1...
7.
Yoshitomi H, Lee K, Yao K, Shin S, Zhang T, Wang Q, et al.
Cancer Res . 2020 Nov; 81(4):945-955. PMID: 33184107
The () gene is well known as a chameleon gene. It plays a role as a tumor suppressor in Wilms' tumor but also acts as an oncogene in other cancers....
8.
Jakhar R, Sharma C, Paul S, Kang S
Int Immunopharmacol . 2018 Oct; 65:268-278. PMID: 30359933
In this study, the immunomodulatory effects of astemizole (AST) against lipopolysaccharide (LPS) mediated T cell proliferation and induction of inflammation in RAW macrophages (in vitro), and zebrafish larvae (in vivo)...
9.
Bhardwaj M, Cho H, Paul S, Jakhar R, Khan I, Lee S, et al.
Oncotarget . 2018 Feb; 9(3):3278-3291. PMID: 29423046
Cancer treatment is limited due to the diverse multidrug resistance acquired by cancer cells and the collateral damage caused to adjacent normal cells by chemotherapy. The flavonoid compound vitexin exhibits...
10.
Bhardwaj M, Paul S, Jakhar R, Khan I, Kang J, Kim H, et al.
Oncotarget . 2018 Jan; 8(68):112426-112441. PMID: 29348836
Heat shock transcription factor-1 (HSF-1) guards the cancerous cells proteome against the alterations in protein homeostasis generated by their hostile tumor microenvironment. Contrasting with the classical induction of heat shock...