Sorin Istrail
Overview
Explore the profile of Sorin Istrail including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
42
Citations
1203
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0
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Recent Articles
1.
Pevzner P, Vingron M, Reidys C, Sun F, Istrail S
J Comput Biol
. 2022 Jun;
29(7):601-615.
PMID: 35727100
On the occasion of Dr. Michael Waterman's 80th birthday, we review his major contributions to the field of computational biology and bioinformatics including the famous Smith-Waterman algorithm for sequence alignment,...
2.
Armanious D, Schuster J, Tollefson G, Agudelo A, DeWan A, Istrail S, et al.
Genomics
. 2020 Jul;
112(6):4288-4296.
PMID: 32702417
We posit the likely architecture of complex diseases is that subgroups of patients share variants in genes in specific networks which are sufficient to give rise to a shared phenotype....
3.
Alpay B, Demetci P, Istrail S, Aguiar D
Bioinformatics
. 2020 Jul;
36(Suppl_1):i194-i202.
PMID: 32657373
Motivation: Genome-wide association studies (GWAS) have discovered thousands of significant genetic effects on disease phenotypes. By considering gene expression as the intermediary between genotype and disease phenotype, expression quantitative trait...
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Huang A, Hogan J, Luo X, DeLong A, Saravanan S, Wu Y, et al.
Open Forum Infect Dis
. 2016 Jul;
3(2):ofv158.
PMID: 27419147
Background. Human immunodeficiency virus (HIV)-1 drug resistance mutations (DRMs) often accompany treatment failure. Although subtype differences are widely studied, DRM comparisons between subtypes either focus on specific geographic regions or...
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McDowell I, Nikapitiya C, Aguiar D, Lane C, Istrail S, Gomez-Chiarri M
PLoS One
. 2014 Aug;
9(8):e105097.
PMID: 25122115
The American oyster Crassostrea virginica, an ecologically and economically important estuarine organism, can suffer high mortalities in areas in the Northeast United States due to Roseovarius Oyster Disease (ROD), caused...
10.
Aguiar D, Wong W, Istrail S
Pac Symp Biocomput
. 2013 Dec;
:3-14.
PMID: 24297529
The growing availability of inexpensive high-throughput sequence data is enabling researchers to sequence tumor populations within a single individual at high coverage. But, cancer genome sequence evolution and mutational phenomena...