Soren Steffensen
Overview
Explore the profile of Soren Steffensen including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
7
Citations
258
Followers
0
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Recent Articles
1.
De Tavernier E, Detalle L, Morizzo E, Roobrouck A, De Taeye S, Rieger M, et al.
J Biol Chem
. 2016 May;
291(29):15243-55.
PMID: 27226529
Improving potencies through concomitant blockage of multiple epitopes and avid binding by fusing multiple (different) monovalent Nanobody building blocks via linker sequences into one multivalent polypeptide chain is an elegant...
2.
Koh W, Steffensen S, Gonzalez-Pajuelo M, Hoorelbeke B, Gorlani A, Szynol A, et al.
J Biol Chem
. 2010 Apr;
285(25):19116-24.
PMID: 20400507
Recently, we described llama antibody fragments (VHH) that can neutralize human immunodeficiency virus, type 1 (HIV-1). These VHH were obtained after selective elution of phages carrying an immune library raised...
3.
Martins T, Maia A, Steffensen S, Sunkel C
EMBO J
. 2009 Jan;
28(3):234-47.
PMID: 19131964
Sgt1 was described previously in yeast and humans to be a Hsp90 co-chaperone and required for kinetochore assembly. We have identified a mutant allele of Sgt1 in Drosophila and characterized...
4.
Malmanche N, Owen S, Gegick S, Steffensen S, Tomkiel J, Sunkel C
Curr Biol
. 2007 Aug;
17(17):1489-97.
PMID: 17702574
The partially conserved Mad3/BubR1 protein is required during mitosis for the spindle assembly checkpoint (SAC). In meiosis, depletion causes an accelerated transit through prophase I and missegregation of achiasmate chromosomes...
5.
Savvidou E, Cobbe N, Steffensen S, Cotterill S, Heck M
J Cell Sci
. 2005 Jun;
118(Pt 11):2529-43.
PMID: 15923665
The precise mechanism of chromosome condensation and decondensation remains a mystery, despite progress over the last 20 years aimed at identifying components essential to the mitotic compaction of the genome....
6.
Poot R, Bozhenok L, van den Berg D, Steffensen S, Ferreira F, Grimaldi M, et al.
Nat Cell Biol
. 2004 Nov;
6(12):1236-44.
PMID: 15543136
Chromatin states have to be faithfully duplicated during DNA replication to maintain cell identity. It is unclear whether or how ATP-dependent chromatin-remodelling factors are involved in this process. Here we...
7.
Agostinho M, Rino J, Braga J, Ferreira F, Steffensen S, Ferreira J
Mol Biol Cell
. 2004 Feb;
15(5):2388-400.
PMID: 14978217
Mammalian topoisomerase IIalpha (topo IIalpha) plays a vital role in the removal of topological complexities left on DNA during S phase. Here, we developed a new assay to selectively identify...