Sophie Petropoulos
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Explore the profile of Sophie Petropoulos including associated specialties, affiliations and a list of published articles.
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51
Citations
1740
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Recent Articles
1.
Author Correction: A comprehensive human embryo reference tool using single-cell RNA-sequencing data
Zhao C, Plaza Reyes A, Schell J, Weltner J, Ortega N, Zheng Y, et al.
Nat Methods
. 2025 Jan;
22(3):636.
PMID: 39856235
No abstract available.
2.
Zhao C, Plaza Reyes A, Schell J, Weltner J, Ortega N, Zheng Y, et al.
Nat Methods
. 2024 Nov;
22(1):193-206.
PMID: 39543283
Stem cell-based embryo models offer unprecedented experimental tools for studying early human development. The usefulness of embryo models hinges on their molecular, cellular and structural fidelities to their in vivo...
3.
Russell S, Zhao C, Biondic S, Menezes K, Hagemann-Jensen M, Librach C, et al.
Nat Commun
. 2024 Oct;
15(1):8634.
PMID: 39367016
Understanding the molecular circuitries that govern early embryogenesis is important, yet our knowledge of these in human preimplantation development remains limited. Small non-coding RNAs (sncRNAs) can regulate gene expression and...
4.
Clark A, Goolam M, Hanna J, Long K, Nicol D, Petropoulos S, et al.
Development
. 2024 Sep;
151(17).
PMID: 39279534
In the companion Perspective 'Past and future of human developmental biology' (Hopwood, 2024), historian Nick Hopwood proposes that the field of human developmental biology has gone through periods of attention...
5.
Li Y, Sun L, Chen R, Ni W, Liang Y, Zhang H, et al.
ACS Cent Sci
. 2024 Jan;
10(1):184-198.
PMID: 38292600
Nonhealing skin wounds are a problematic complication associated with diabetes. Therapeutic gases delivered by biomaterials have demonstrated powerful wound healing capabilities. However, the cellular responses and heterogeneity in the skin...
6.
Esfahani S, Zheng Y, Arabpour A, Irizarry A, Kobayashi N, Xue X, et al.
Nat Commun
. 2024 Jan;
15(1):167.
PMID: 38167821
Primordial germ cells (PGCs) are the embryonic precursors of sperm and eggs. They transmit genetic and epigenetic information across generations. Given the prominent role of germline defects in diseases such...
7.
Biondic S, Petropoulos S
Yale J Biol Med
. 2024 Jan;
96(4):481-494.
PMID: 38161584
Proper formation of the blastocyst, including the specification of the first embryonic cellular lineages, is required to ensure healthy embryo development and can significantly impact the success of assisted reproductive...
8.
Oldak B, Wildschutz E, Bondarenko V, Comar M, Zhao C, Aguilera-Castrejon A, et al.
Nature
. 2023 Sep;
622(7983):562-573.
PMID: 37673118
The ability to study human post-implantation development remains limited owing to ethical and technical challenges associated with intrauterine development after implantation. Embryo-like models with spatially organized morphogenesis and structure of...
9.
Vandal K, Biondic S, Canizo J, Petropoulos S
Methods Mol Biol
. 2023 Jul;
2767:293-305.
PMID: 37418145
Single-cell genomics allow the characterization and quantification of molecular heterogeneity from a wide variety of tissues. Here, we describe the manual dissociation and collection of single cells, a method adapted...
10.
Canizo J, Biondic S, Lenghan K, Petropoulos S
Methods Mol Biol
. 2023 Jun;
2767:275-292.
PMID: 37284942
Studying various animal models is important for comparative biology and to better understand evolutionary development. Furthermore, when aiming to translate findings to human development, it is crucial to select an...