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Sophie Howarth

Explore the profile of Sophie Howarth including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 65
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Recent Articles
1.
Galligan D, Payne L, Sullivan D, Bhadravathi Lokeshappa M, Ziser L, Nunn L, et al.
BMJ Open . 2025 Mar; 15(3):e091676. PMID: 40081998
Purpose: Children with neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) face a range of challenges which impact their daily functioning and that of...
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Howarth S, Ho T, Wimbury J, Casey R
Clin Endocrinol (Oxf) . 2024 Dec; 102(3):344-354. PMID: 39740208
The management of hypoglycaemia is pivotal in the care of patients with insulinoma. Blood glucose monitoring and regulation needs careful attention pre- and peri-operatively for patients undergoing surgical resection and...
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Howarth S, Sneddon G, Allinson K, Razvi S, Mitchell A, Pearce S
Eur J Endocrinol . 2023 Jan; 188(1). PMID: 36651163
Autoimmune Addison's disease (AAD) arises from a complex interplay between multiple genetic susceptibility polymorphisms and environmental factors. The first genome wide association study (GWAS) with patients from Scandinavian Addison's registries...
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Howarth S, Giovanelli L, Napier C, Pearce S
Endocr Connect . 2022 Nov; 12(1). PMID: 36398876
Autoimmune Addison's disease (AAD) is defined as primary adrenal insufficiency due to immune-mediated destruction of the adrenal cortex. This destruction of steroid-producing cells has historically been thought of as an...
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Howarth S, Quinton R, Mohammed A
Clin Endocrinol (Oxf) . 2022 Nov; 98(3):454-456. PMID: 36342078
No abstract available.
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Howarth S, Quinton R
BMJ Case Rep . 2022 Aug; 15(8). PMID: 35977751
A woman in her 50s with Turner syndrome was referred to the endocrine clinic, having been unaware of her diagnosis until she received a shielding letter from the UK government...
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Duncan C, Skouboe M, Howarth S, Hollensen A, Chen R, Borresen M, et al.
J Exp Med . 2022 Apr; 219(6). PMID: 35442417
Type I interferons (IFN-I) play a critical role in human antiviral immunity, as demonstrated by the exceptionally rare deleterious variants of IFNAR1 or IFNAR2. We investigated five children from Greenland,...
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Gothe F, Howarth S, Duncan C, Hambleton S
Curr Opin Immunol . 2021 Jun; 72:167-175. PMID: 34107321
Live attenuated viral vaccines (LAV) have saved millions of lives globally through their capacity to elicit strong, cross-reactive and enduring adaptive immune responses. However, LAV can also act as a...
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McCarthy A, Howarth S, Khoo S, Hale J, Oddy S, Halsall D, et al.
Endocrinol Diabetes Metab Case Rep . 2019 May; 2019. PMID: 31096181
Primary hyperparathyroidism (PHPT) is characterised by the overproduction of parathyroid hormone (PTH) due to parathyroid hyperplasia, adenoma or carcinoma and results in hypercalcaemia and a raised or inappropriately normal PTH....