Sophie E Walker
Overview
Explore the profile of Sophie E Walker including associated specialties, affiliations and a list of published articles.
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10
Citations
116
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Recent Articles
1.
Monari S, Guillot de Suduiraut I, Grosse J, Zanoletti O, Walker S, Mesquita M, et al.
Biol Psychiatry
. 2023 Sep;
95(8):762-773.
PMID: 37743003
Background: Understanding why only a subset of trauma-exposed individuals develop posttraumatic stress disorder is critical for advancing clinical strategies. A few behavioral (deficits in fear extinction) and biological (blunted glucocorticoid...
2.
Dixon C, Walker S, Swinny J, Belelli D, Lambert J, King S, et al.
Behav Pharmacol
. 2019 Feb;
30(2 and 3-Spec Issue):272-281.
PMID: 30724801
Early-life stress (ELS) is known to exert long-term effects on brain function, with resulting deleterious consequences for several aspects of mental health, including the development of addiction to drugs of...
3.
Walker S, Wood T, Cash D, Mesquita M, Williams S, Sandi C
Eur J Neurosci
. 2018 Jul;
48(2):1818-1832.
PMID: 29961949
Exposure to early adversity is implicated in the development of aggressive behaviour later in life in some but not all individuals. The reasons for the variability in response to such...
4.
Walker S, Sandi C
Stress
. 2018 Feb;
21(5):433-442.
PMID: 29415604
Experience of adversity early in life and dysregulation of hypothalamus-pituitary-adrenocortical (HPA) axis activity are risk factors often independently associated with the development of psychopathological disorders, including depression, PTSD and pathological...
5.
Walker S, Zanoletti O, Guillot de Suduiraut I, Sandi C
Psychoneuroendocrinology
. 2017 Jun;
84:1-10.
PMID: 28647673
Glucocorticoids coordinate responses that enable an individual to cope with stressful challenges and, additionally, mediate adaptation following cessation of a stressor. There are important individual differences in the magnitude of...
6.
Kukalev A, Ng Y, Ju L, Saidi A, Lane S, Mondragon A, et al.
Cereb Cortex
. 2017 Apr;
27(1):11-23.
PMID: 28365778
In mitotic cells, the cyclin-dependent kinase (CDK) subunit protein CKS1 regulates S phase entry by mediating degradation of the CDK inhibitor p27. Although mature neurons lack mitotic CDKs, we found...
7.
Walker S, Papilloud A, Huzard D, Sandi C
Neurosci Biobehav Rev
. 2016 Oct;
91:138-152.
PMID: 27751733
Aggressive behavior is not uniform, including proactive and reactive forms of aggression. Aberrant functioning of the hypothalamic-pituitary-adrenal (HPA) axis is frequently associated with abnormal aggression. Here, we review the rodent...
8.
Anstee Q, Knapp S, Maguire E, Hosie A, Thomas P, Mortensen M, et al.
Nat Commun
. 2013 Nov;
4:2816.
PMID: 24281383
Alcohol dependence is a common, complex and debilitating disorder with genetic and environmental influences. Here we show that alcohol consumption increases following mutations to the γ-aminobutyric acidA receptor (GABAAR) β1...
9.
Dixon C, Walker S, King S, Stephens D
PLoS One
. 2012 Nov;
7(10):e47135.
PMID: 23115637
Human genetic studies have suggested that polymorphisms of the GABRA2 gene encoding the GABA(A) α2-subunit are associated with ethanol dependence. Variations in this gene also convey sensitivity to the subjective...
10.
Walker S, Pena-Oliver Y, Stephens D
Psychopharmacology (Berl)
. 2011 Apr;
217(3):433-42.
PMID: 21509502
Rationale: There is extensive evidence that alcoholism and impulsivity are related, but the direction of causality is unclear. Objectives: The aim of the present investigation was to study the effects...