Sophie C James
Overview
Explore the profile of Sophie C James including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
14
Followers
0
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Recent Articles
1.
Dembitz V, Lawson H, Burt R, Natani S, Philippe C, James S, et al.
Leukemia
. 2024 Aug;
38(11):2395-2409.
PMID: 39187579
Identification of specific and therapeutically actionable vulnerabilities, ideally present across multiple mutational backgrounds, is needed to improve acute myeloid leukemia (AML) patients' outcomes. We identify stearoyl-CoA desaturase (SCD), the key...
2.
Dembitz V, Durko J, Campos J, James S, Lawson H, Kranc K, et al.
Hemasphere
. 2024 Mar;
8(1):e28.
PMID: 38434525
No abstract available.
3.
Tsutsumi N, Masoumi Z, James S, Tucker J, Winkelmann H, Grey W, et al.
Cell
. 2023 Aug;
186(19):4189-4203.e22.
PMID: 37633268
Thrombopoietin (THPO or TPO) is an essential cytokine for hematopoietic stem cell (HSC) maintenance and megakaryocyte differentiation. Here, we report the 3.4 Å resolution cryoelectron microscopy structure of the extracellular...
4.
Woodley K, Dillingh L, Giotopoulos G, Madrigal P, Rattigan K, Philippe C, et al.
Nat Commun
. 2023 Apr;
14(1):2132.
PMID: 37059720
Resistance to standard and novel therapies remains the main obstacle to cure in acute myeloid leukaemia (AML) and is often driven by metabolic adaptations which are therapeutically actionable. Here we...