Sophia Yancopoulos
Overview
Explore the profile of Sophia Yancopoulos including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
564
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0
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Recent Articles
1.
Vergani S, Bagnara D, Agathangelidis A, Ng A, Ferrer G, Mazzarello A, et al.
Front Oncol
. 2023 Apr;
13:1112879.
PMID: 37007084
Introduction: The leukemic cells of patients with chronic lymphocytic leukemia (CLL) are often unique, expressing remarkably similar IGHV-IGHD-IGHJ gene rearrangements, "stereotyped BCRs". The B-cell receptors (BCRs) on CLL cells are...
2.
Calissano C, Damle R, Marsilio S, Yan X, Yancopoulos S, Hayes G, et al.
Mol Med
. 2022 Mar;
28(1):35.
PMID: 35291936
No abstract available.
3.
Ferrer G, Jung B, Chiu P, Aslam R, Palacios F, Mazzarello A, et al.
Leukemia
. 2021 May;
35(11):3163-3175.
PMID: 33935280
Cancer pathogenesis involves the interplay of tumor- and microenvironment-derived stimuli. Here we focused on the influence of an immunomodulatory cell type, myeloid-derived suppressor cells (MDSCs), and their lineage-related subtypes on...
4.
McCARTHY B, Yancopoulos S, Tipping M, Yan X, Wang X, Bennett F, et al.
Immunol Res
. 2015 Aug;
63(1-3):90-100.
PMID: 26318878
Chronic lymphocytic leukemia (CLL) is a clonal disease of B lymphocytes manifesting as an absolute lymphocytosis in the blood. However, not all lymphocytoses are leukemic. In addition, first-degree relatives of...
5.
Chen S, Batliwalla F, Holodick N, Yan X, Yancopoulos S, Croce C, et al.
Proc Natl Acad Sci U S A
. 2013 Apr;
110(16):E1500-7.
PMID: 23550156
(Auto)antigen engagement by the B-cell receptor (BCR) and possibly the sites where this occurs influence the outcome of chronic lymphocytic leukemia (CLL). To test if selection for autoreactivity leads to...
6.
Attie O, Darling A, Yancopoulos S
BMC Bioinformatics
. 2011 Dec;
12 Suppl 9:S1.
PMID: 22151330
Background: During evolution, large-scale genome rearrangements of chromosomes shuffle the order of homologous genome sequences ("synteny blocks") across species. Some years ago, a controversy erupted in genome rearrangement studies over...
7.
Calissano C, Damle R, Marsilio S, Yan X, Yancopoulos S, Hayes G, et al.
Mol Med
. 2011 Oct;
17(11-12):1374-82.
PMID: 21968788
The failure of chemotherapeutic regimens to eradicate cancers often results from the outgrowth of minor subclones with more dangerous genomic abnormalities or with self-renewing capacity. To explore such intratumor complexities...
8.
Yan X, Dozmorov I, Li W, Yancopoulos S, Sison C, Centola M, et al.
Blood
. 2011 Sep;
118(19):5201-10.
PMID: 21911837
Individual cytokines and groups of cytokines that might represent networks in chronic lymphocytic leukemia (CLL) were analyzed and their prognostic values determined. Serum levels of 23 cytokines were measured in...
9.
Yancopoulos S, Friedberg R
J Comput Biol
. 2009 Oct;
16(10):1311-38.
PMID: 19803734
We extend the double cut and join operation (DCJ) paradigm to perform genome rearrangements on pairs of genomes having unequal gene content and/or multiple copies by permitting genes in one...
10.
Seiler T, Woelfle M, Yancopoulos S, Catera R, Li W, Hatzi K, et al.
Blood
. 2009 Aug;
114(17):3615-24.
PMID: 19690339
Despite a wealth of information about the structure of surface membrane immunoglobulin (smIg) on chronic lymphocytic leukemia (CLL) cells, little is known about epitopes reacting with their binding sites. Probing...