Soo Hyeon Lee
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Explore the profile of Soo Hyeon Lee including associated specialties, affiliations and a list of published articles.
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56
Citations
844
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Recent Articles
1.
Mo S, Lee S, Choi C, Sunwoo Y, Shin S, Choi Y
Microorganisms
. 2025 Jan;
13(1.
PMID: 39858904
A comprehensive pharmacovigilance surveillance on antibacterials is lacking. This study aims to investigate safety signals of antibacterial-related adverse drug events (ADEs) with seriousness and to identify predictors of serious ADEs....
2.
Lee Y, Lee S, Kim S, Kim S, Lee S, Park S, et al.
Leukemia
. 2024 Jul;
38(10):2150-2161.
PMID: 39080354
Chronic myeloid leukemia (CML), caused by BCR::ABL1 fusion gene, is known to regulate disease progression by altering the expression of genes. However, the molecular mechanisms underlying these changes are largely...
3.
Sunwoo Y, Eom S, Yun J, Kim Y, Lee J, Lee S, et al.
Medicina (Kaunas)
. 2024 Jul;
60(7).
PMID: 39064457
: Despite high incidences of cognitive impairment with aging, evidence on the prevalence and the seriousness of drug-induced cognitive impairment is limited. This study aims to evaluate the prevalence and...
4.
Lee S, Lee S, Choi N, Kim J, Kweon J, Miller K, et al.
Nucleic Acids Res
. 2024 Jun;
52(15):8643-8660.
PMID: 38936834
R-loops cause genome instability, disrupting normal cellular functions. Histone acetylation, particularly by p300/CBP-associated factor (PCAF), is essential for maintaining genome stability and regulating cellular processes. Understanding how R-loop formation and...
5.
Petruncio G, Lee K, Girgis M, Shellnutt Z, Beaulac Z, Xiang J, et al.
Eur J Med Chem
. 2024 May;
272:116459.
PMID: 38704942
Activation of the aminopeptidase (AP) activity of leukotriene A hydrolase (LTAH) presents a potential therapeutic strategy for resolving chronic inflammation. Previously, ARM1 and derivatives were found to activate the AP...
6.
Bigini F, Lee S, Sun Y, Sun Y, Mahajan V
Vision Res
. 2023 Sep;
213:108317.
PMID: 37722240
Gene therapy is a flourishing field with the potential to revolutionize the treatment of genetic diseases. The emergence of CRISPR-Cas9 has significantly advanced targeted and efficient genome editing. Although CRISPR-Cas9...
7.
Han G, Noh D, Lee H, Lee S, Kim S, Yoon H, et al.
Adv Drug Deliv Rev
. 2023 Jun;
199:114973.
PMID: 37369262
RNA vaccines have demonstrated their ability to solve the issues posed by the COVID-19 pandemic. This success has led to the renaissance of research into mRNA and their nanoformulations as...
8.
Lee K, Ali N, Lee S, Zhang Z, Burdick M, Beaulac Z, et al.
Sci Rep
. 2022 Jun;
12(1):9443.
PMID: 35676292
The aminopeptidase activity (AP) of the leukotriene A hydrolase (LTAH) enzyme has emerged as a therapeutic target to modulate host immunity. Initial reports focused on the benefits of augmenting the...
9.
Vu J, Wang E, Wu J, Sun Y, Velez G, Bassuk A, et al.
Trends Mol Med
. 2022 May;
28(8):644-661.
PMID: 35641420
Ophthalmic neurodegenerative diseases encompass a wide array of molecular pathologies unified by calpain dysregulation. Calpains are calcium-dependent proteases that perpetuate cellular death and inflammation when hyperactivated. Calpain inhibition trials in...
10.
Lin C, Sun Y, Lee S, Mujica E, Kunchur C, Wu M, et al.
STAR Protoc
. 2022 Feb;
3(1):101143.
PMID: 35141566
Ocular drug implants (ODIs) are beneficial for treating ocular diseases. However, the lack of a robust injection approach for small-eyed model organisms has been a major technical limitation in developing...