Soo Han Bae
Overview
Explore the profile of Soo Han Bae including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
5713
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Recent Articles
11.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
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Kim Y, Jeung H, Cheong J, Song J, Bae S, Lee J, et al.
Yonsei Med J
. 2020 Sep;
61(9):762-773.
PMID: 32882760
Purpose: Pharmacological inhibition of mutant isocitrate dehydrogenase (IDH) reduces R-2-hydroxyglutarate (2-HG) levels and restores cellular differentiation in vivo and in vitro. The IDH2 inhibitor enasidenib (AG-221) has been approved by...
15.
Lee M, Luo H, Bae S, San-Miguel A
Oxid Med Cell Longev
. 2020 May;
2020:4684890.
PMID: 32377299
No abstract available.
16.
Lee Y, Park J, Lee D, Han J, Bae S
FASEB J
. 2020 Jan;
34(1):898-911.
PMID: 31914598
Adipogenesis, a critical process that converts adipocyte precursors into adipocytes, is considered a potential therapeutic target for the treatment of obesity. Ezetimibe, a drug approved by the United States Food...
17.
Lee D, Park J, Lee Y, Han J, Lee D, Kwon S, et al.
Autophagy
. 2020 Jan;
16(11):1949-1973.
PMID: 31913745
Lipotoxicity, induced by saturated fatty acid (SFA)-mediated cell death, plays an important role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). The KEAP1 (kelch like ECH associated protein 1)-NFE2L2/NRF2...
18.
Bahn G, Park J, Yun U, Lee Y, Choi Y, Park J, et al.
Proc Natl Acad Sci U S A
. 2019 Jun;
116(25):12516-12523.
PMID: 31164420
BACE1 is the rate-limiting enzyme for amyloid-β peptides (Aβ) generation, a key event in the pathogenesis of Alzheimer's disease (AD). By an unknown mechanism, levels of and a mRNA-stabilizing antisense...
19.
Park J, Lee Y, Lee D, Bae S
Free Radic Biol Med
. 2019 Apr;
137:143-157.
PMID: 31035006
Nonalcoholic steatohepatitis (NASH) is a common liver disease associated with metabolic disorders, including obesity and type 2 diabetes (T2D). Despite its worldwide prevalence, there are no effective drugs for the...
20.
Park J, Lee D, Lee Y, Oh E, Bae K, Oh K, et al.
Autophagy
. 2019 Mar;
16(1):86-105.
PMID: 30907226
Saturated fatty acid (SFA)-induced lipotoxicity is caused by the accumulation of reactive oxygen species (ROS), which is associated with damaged mitochondria. Moreover, lipotoxicity is crucial for the progression of nonalcoholic...